Lineage for Protein: 2-oxoisovalerate dehydrogenase (E1B), PP module
- Root: SCOP 1.67
Class c: Alpha and beta proteins (a/b) [51349] (130 folds) 
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) 
there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
Family c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module [88766] (3 proteins)
parent family to TK and PFOR
heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module
Protein 2-oxoisovalerate dehydrogenase (E1B), PP module [88769] (1 species)
chain A is alpha-subunit and chain B is beta-subunit
Species:
Pseudomonas putida [TaxId:303] [88770] (1 PDB entry) - Domain for 1qs0:
Domain d1qs0a_: 1qs0 A: [31829]
Other proteins in same PDB: d1qs0b1, d1qs0b2
complexed with hri, mg, tdp
- Domain for 1qs0:
More info for Protein 2-oxoisovalerate dehydrogenase (E1B), PP module from c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module
Timeline for Protein 2-oxoisovalerate dehydrogenase (E1B), PP module from c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module:
- Protein 2-oxoisovalerate dehydrogenase (E1B), PP module from c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module first appeared in SCOP 1.65
- Protein 2-oxoisovalerate dehydrogenase (E1B), PP module from c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module appears in SCOP 1.69
- Protein 2-oxoisovalerate dehydrogenase (E1B), PP module from c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module appears in the current release, SCOPe 2.08