![]() | Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
![]() | Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465 |
![]() | Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) ![]() there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules |
![]() | Family c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module [88766] (5 proteins) parent family to TK and PFOR heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module |
![]() | Protein 2-oxoisovalerate dehydrogenase (E1B), PP module [88769] (1 species) chain A is alpha-subunit and chain B is beta-subunit |
![]() | Pseudomonas putida [TaxId:303] [88770] (1 PDB entry) |
![]() | Domain d1qs0a_: 1qs0 A: [31829] Other proteins in same PDB: d1qs0b1, d1qs0b2 complexed with coi, mg, tdp |
Timeline for Protein 2-oxoisovalerate dehydrogenase (E1B), PP module from c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module: