Class c: Alpha and beta proteins (a/b) [51349] (136 folds) |
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465 |
Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules |
Family c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module [88766] (3 proteins) parent family to TK and PFOR heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module |
Protein Branched-chain alpha-keto acid dehydrogenase, PP module [88767] (2 species) |
Species Human (Homo sapiens) [TaxId:9606] [88768] (8 PDB entries) |
Domain d1dtwa_: 1dtw A: [31827] Other proteins in same PDB: d1dtwb1, d1dtwb2 |
Domain d1olsa_: 1ols A: [93331] Other proteins in same PDB: d1olsb1, d1olsb2 |
Domain d1olua_: 1olu A: [93335] Other proteins in same PDB: d1olub1, d1olub2 |
Domain d1olxa_: 1olx A: [93338] Other proteins in same PDB: d1olxb1, d1olxb2 |
Domain d1v11a_: 1v11 A: [108227] Other proteins in same PDB: d1v11b1, d1v11b2 |
Domain d1v16a_: 1v16 A: [108240] Other proteins in same PDB: d1v16b1, d1v16b2 |
Domain d1v1ma_: 1v1m A: [108261] Other proteins in same PDB: d1v1mb1, d1v1mb2 |
Domain d1v1ra_: 1v1r A: [108272] Other proteins in same PDB: d1v1rb1, d1v1rb2 |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.36.1.11 Branched-chain alpha-keto acid dehydrogenase, PP module: