Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2108258Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 2108259Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 2108723Family c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module [88766] (5 protein domains)
    parent family to TK and PFOR
    heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module
  6. 2108727Protein Branched-chain alpha-keto acid dehydrogenase, PP module [88767] (2 species)
  7. 2108728Species Human (Homo sapiens) [TaxId:9606] [88768] (19 PDB entries)
    Uniprot P12694 52-445

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1dtw:
  2. Domain(s) for 1ols:
  3. Domain(s) for 1olu:
  4. Domain(s) for 1olx:
  5. Domain(s) for 1u5b:
  6. Domain(s) for 1v11:
  7. Domain(s) for 1v16:
  8. Domain(s) for 1v1m:
  9. Domain(s) for 1v1r:
  10. Domain(s) for 1x7w:
  11. Domain(s) for 1x7x:
  12. Domain(s) for 1x7y:
  13. Domain(s) for 1x7z:
  14. Domain(s) for 1x80:
  15. Domain(s) for 2bfb:
  16. Domain(s) for 2bfc:
  17. Domain(s) for 2bfd:
  18. Domain(s) for 2bfe:
  19. Domain(s) for 2bff:

More info for Species Human (Homo sapiens) [TaxId:9606] from c.36.1.11 Branched-chain alpha-keto acid dehydrogenase, PP module

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.36.1.11 Branched-chain alpha-keto acid dehydrogenase, PP module: