Lineage for Protein: Branched-chain alpha-keto acid dehydrogenase, PP module

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2108258Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 2108259Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 2108723Family c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module [88766] (5 protein domains)
    parent family to TK and PFOR
    heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module
  6. 2108727Protein Branched-chain alpha-keto acid dehydrogenase, PP module [88767] (2 species)

Species:

  1. 2108728Human (Homo sapiens) [TaxId:9606] [88768] (19 PDB entries)
    Uniprot P12694 52-445
    1. Domain for 1dtw:
    2. Domain for 1ols:
    3. Domain for 1olu:
    4. Domain for 1olx:
    5. Domain for 1u5b:
    6. Domain for 1v11:
    7. Domain for 1v16:
    8. Domain for 1v1m:
    9. Domain for 1v1r:
    10. Domain for 1x7w:
    11. Domain for 1x7x:
    12. Domain for 1x7y:
    13. Domain for 1x7z:
    14. Domain for 1x80:
    15. Domain for 2bfb:
    16. Domain for 2bfc:
    17. Domain for 2bfd:
    18. Domain for 2bfe:
    19. Domain for 2bff:
  2. 2108748Thermus thermophilus [TaxId:274] [102337] (4 PDB entries)
    1. Domains for 1um9:
      1. 2108753Domain d1um9a_: 1um9 A: [99581]
        Other proteins in same PDB: d1um9b1, d1um9b2, d1um9d1, d1um9d2
        complexed with so4
      2. 2108754Domain d1um9c_: 1um9 C: [99584]
        Other proteins in same PDB: d1um9b1, d1um9b2, d1um9d1, d1um9d2
        complexed with so4
    2. Domains for 1umb:
      1. 2108751Domain d1umba_: 1umb A: [99587]
        Other proteins in same PDB: d1umbb1, d1umbb2, d1umbd1, d1umbd2
        complexed with mg, tdp
      2. 2108752Domain d1umbc_: 1umb C: [99590]
        Other proteins in same PDB: d1umbb1, d1umbb2, d1umbd1, d1umbd2
        complexed with mg, tdp
    3. Domains for 1umc:
      1. 2108755Domain d1umca_: 1umc A: [99593]
        Other proteins in same PDB: d1umcb1, d1umcb2, d1umcd1, d1umcd2
        complexed with 4mv, mg, tdp
      2. 2108756Domain d1umcc_: 1umc C: [99596]
        Other proteins in same PDB: d1umcb1, d1umcb2, d1umcd1, d1umcd2
        complexed with 4mv, mg, tdp
    4. Domains for 1umd:
      1. 2108749Domain d1umda_: 1umd A: [99599]
        Other proteins in same PDB: d1umdb1, d1umdb2, d1umdd1, d1umdd2
        complexed with coi, mg, tdp
      2. 2108750Domain d1umdc_: 1umd C: [99602]
        Other proteins in same PDB: d1umdb1, d1umdb2, d1umdd1, d1umdd2
        complexed with coi, mg, tdp

More info for Protein Branched-chain alpha-keto acid dehydrogenase, PP module from c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module

Timeline for Protein Branched-chain alpha-keto acid dehydrogenase, PP module from c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module:

  • Protein Branched-chain alpha-keto acid dehydrogenase, PP module from c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module first appeared in SCOP 1.65
  • Protein Branched-chain alpha-keto acid dehydrogenase, PP module from c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module appears in SCOPe 2.05