Lineage for Species: Escherichia coli [TaxId: 562]

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2108258Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 2108259Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 2108664Family c.36.1.10: TK-like PP module [88760] (3 protein domains)
    different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain
  6. 2108665Protein Pyruvate dehydrogenase E1 component, PP module [88764] (1 species)
    E1A and E1B fused together in a single-chain protein
  7. 2108666Species Escherichia coli [TaxId:562] [88765] (8 PDB entries)

PDB entries in Species: Escherichia coli [TaxId: 562]:

  1. Domain(s) for 1l8a:
    1. 2108673Domain d1l8aa1: 1l8a A:56-470 [73677]
      Other proteins in same PDB: d1l8aa2, d1l8aa3, d1l8ab2, d1l8ab3
      complexed with mg, tdp
    2. 2108674Domain d1l8ab1: 1l8a B:56-470 [73680]
      Other proteins in same PDB: d1l8aa2, d1l8aa3, d1l8ab2, d1l8ab3
      complexed with mg, tdp
  2. Domain(s) for 1rp7:
    1. 2108679Domain d1rp7a2: 1rp7 A:56-470 [97703]
      Other proteins in same PDB: d1rp7a1, d1rp7a3, d1rp7b1, d1rp7b3
      complexed with mg, tzd
    2. 2108680Domain d1rp7b2: 1rp7 B:56-470 [97706]
      Other proteins in same PDB: d1rp7a1, d1rp7a3, d1rp7b1, d1rp7b3
      complexed with mg, tzd
  3. Domain(s) for 2g25:
    1. 2108677Domain d2g25a2: 2g25 A:56-470 [134524]
      Other proteins in same PDB: d2g25a1, d2g25a3, d2g25b1, d2g25b3
      automated match to d1l8aa1
      complexed with mg, po4, tdk
    2. 2108678Domain d2g25b2: 2g25 B:56-470 [134527]
      Other proteins in same PDB: d2g25a1, d2g25a3, d2g25b1, d2g25b3
      automated match to d1l8aa1
      complexed with mg, po4, tdk
  4. Domain(s) for 2g28:
    1. 2108675Domain d2g28a2: 2g28 A:56-470 [134530]
      Other proteins in same PDB: d2g28a1, d2g28a3, d2g28b1, d2g28b3
      automated match to d1l8aa1
      complexed with mg, tdk
    2. 2108676Domain d2g28b2: 2g28 B:56-470 [134533]
      Other proteins in same PDB: d2g28a1, d2g28a3, d2g28b1, d2g28b3
      automated match to d1l8aa1
      complexed with mg, tdk
  5. Domain(s) for 2g67:
    1. 2108681Domain d2g67a2: 2g67 A:56-470 [134696]
      Other proteins in same PDB: d2g67a1, d2g67a3, d2g67b1, d2g67b3
      automated match to d1l8aa1
    2. 2108682Domain d2g67b2: 2g67 B:56-470 [134699]
      Other proteins in same PDB: d2g67a1, d2g67a3, d2g67b1, d2g67b3
      automated match to d1l8aa1
  6. Domain(s) for 2iea:
    1. 2108667Domain d2ieaa2: 2iea A:56-470 [137295]
      Other proteins in same PDB: d2ieaa1, d2ieaa3, d2ieab1, d2ieab3
      automated match to d1l8aa1
      complexed with mg, tdp
    2. 2108668Domain d2ieab2: 2iea B:56-470 [137298]
      Other proteins in same PDB: d2ieaa1, d2ieaa3, d2ieab1, d2ieab3
      automated match to d1l8aa1
      complexed with mg, tdp
  7. Domain(s) for 2qta:
    1. 2108671Domain d2qtaa2: 2qta A:56-470 [151334]
      Other proteins in same PDB: d2qtaa1, d2qtaa3, d2qtab1, d2qtab3
      automated match to d2ieaa2
      complexed with mg, tdp; mutant
    2. 2108672Domain d2qtab2: 2qta B:56-470 [151337]
      Other proteins in same PDB: d2qtaa1, d2qtaa3, d2qtab1, d2qtab3
      automated match to d2ieaa2
      complexed with mg, tdp; mutant
  8. Domain(s) for 2qtc:
    1. 2108669Domain d2qtca2: 2qtc A:56-470 [151344]
      Other proteins in same PDB: d2qtca1, d2qtca3, d2qtcb1, d2qtcb3
      automated match to d2ieaa2
      complexed with mg, tdk; mutant
    2. 2108670Domain d2qtcb2: 2qtc B:56-470 [151347]
      Other proteins in same PDB: d2qtca1, d2qtca3, d2qtcb1, d2qtcb3
      automated match to d2ieaa2
      complexed with mg, tdk; mutant

More info for Species Escherichia coli [TaxId:562] from c.36.1.10 Pyruvate dehydrogenase E1 component, PP module

Timeline for Species Escherichia coli [TaxId:562] from c.36.1.10 Pyruvate dehydrogenase E1 component, PP module: