Class c: Alpha and beta proteins (a/b) [51349] (121 folds) |
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465 |
Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules |
Family c.36.1.10: TK-like PP module [88760] (2 proteins) different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain |
Protein Transketolase (TK), PP module [88761] (3 species) |
Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88762] (7 PDB entries) |
Domain d1ay0a1: 1ay0 A:3-337 [31823] Other proteins in same PDB: d1ay0a2, d1ay0a3, d1ay0b2, d1ay0b3 |
Domain d1ay0b1: 1ay0 B:3-337 [31825] Other proteins in same PDB: d1ay0a2, d1ay0a3, d1ay0b2, d1ay0b3 complexed with ca, tpp; mutant |
Domain d1gpua1: 1gpu A:3-337 [65454] Other proteins in same PDB: d1gpua2, d1gpua3, d1gpub2, d1gpub3 |
Domain d1gpub1: 1gpu B:3-337 [65457] Other proteins in same PDB: d1gpua2, d1gpua3, d1gpub2, d1gpub3 complexed with ca, thd |
Domain d1ngsa1: 1ngs A:3-337 [31819] Other proteins in same PDB: d1ngsa2, d1ngsa3, d1ngsb2, d1ngsb3 |
Domain d1ngsb1: 1ngs B:3-337 [31821] Other proteins in same PDB: d1ngsa2, d1ngsa3, d1ngsb2, d1ngsb3 complexed with ca, e4p, tpp |
Domain d1tkaa1: 1tka A:3-337 [31815] Other proteins in same PDB: d1tkaa2, d1tkaa3, d1tkab2, d1tkab3 |
Domain d1tkab1: 1tka B:3-337 [31817] Other proteins in same PDB: d1tkaa2, d1tkaa3, d1tkab2, d1tkab3 complexed with ca, n3t |
Domain d1tkba1: 1tkb A:3-337 [31807] Other proteins in same PDB: d1tkba2, d1tkba3, d1tkbb2, d1tkbb3 |
Domain d1tkbb1: 1tkb B:3-337 [31809] Other proteins in same PDB: d1tkba2, d1tkba3, d1tkbb2, d1tkbb3 complexed with ca, n1t |
Domain d1tkca1: 1tkc A:3-337 [31811] Other proteins in same PDB: d1tkca2, d1tkca3, d1tkcb2, d1tkcb3 |
Domain d1tkcb1: 1tkc B:3-337 [31813] Other proteins in same PDB: d1tkca2, d1tkca3, d1tkcb2, d1tkcb3 complexed with ca, m6t |
Domain d1trka1: 1trk A:3-337 [31803] Other proteins in same PDB: d1trka2, d1trka3, d1trkb2, d1trkb3 |
Domain d1trkb1: 1trk B:3-337 [31805] Other proteins in same PDB: d1trka2, d1trka3, d1trkb2, d1trkb3 complexed with ca, tpp |
Escherichia coli [TaxId:562] [89656] (1 PDB entry) |
Maize (Zea mays) [TaxId:4577] [88763] (1 PDB entry) |
Domain d1itza1: 1itz A:10-347 [76797] Other proteins in same PDB: d1itza2, d1itza3, d1itzb2, d1itzb3, d1itzc2, d1itzc3 |
Domain d1itzb1: 1itz B:10-347 [76800] Other proteins in same PDB: d1itza2, d1itza3, d1itzb2, d1itzb3, d1itzc2, d1itzc3 |
Domain d1itzc1: 1itz C:10-347 [76803] Other proteins in same PDB: d1itza2, d1itza3, d1itzb2, d1itzb3, d1itzc2, d1itzc3 complexed with mg, tpp |
Timeline for Protein Transketolase (TK), PP module from c.36.1.10: TK-like PP module: