Lineage for Protein: Transketolase (TK), PP module

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2108258Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 2108259Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 2108664Family c.36.1.10: TK-like PP module [88760] (3 protein domains)
    different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain
  6. 2108683Protein Transketolase (TK), PP module [88761] (4 species)

Species:

  1. 2108684Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88762] (7 PDB entries)
    1. Domains for 1ay0:
      1. 2108697Domain d1ay0a1: 1ay0 A:3-337 [31823]
        Other proteins in same PDB: d1ay0a2, d1ay0a3, d1ay0b2, d1ay0b3
        complexed with ca, tpp
      2. 2108698Domain d1ay0b1: 1ay0 B:3-337 [31825]
        Other proteins in same PDB: d1ay0a2, d1ay0a3, d1ay0b2, d1ay0b3
        complexed with ca, tpp
    2. Domains for 1gpu:
      1. 2108685Domain d1gpua1: 1gpu A:3-337 [65454]
        Other proteins in same PDB: d1gpua2, d1gpua3, d1gpub2, d1gpub3
        complexed with ca, thd
      2. 2108686Domain d1gpub1: 1gpu B:3-337 [65457]
        Other proteins in same PDB: d1gpua2, d1gpua3, d1gpub2, d1gpub3
        complexed with ca, thd
    3. Domains for 1ngs:
      1. 2108695Domain d1ngsa1: 1ngs A:3-337 [31819]
        Other proteins in same PDB: d1ngsa2, d1ngsa3, d1ngsb2, d1ngsb3
        complexed with ca, e4p, tpp
      2. 2108696Domain d1ngsb1: 1ngs B:3-337 [31821]
        Other proteins in same PDB: d1ngsa2, d1ngsa3, d1ngsb2, d1ngsb3
        complexed with ca, e4p, tpp
    4. Domains for 1tka:
      1. 2108693Domain d1tkaa1: 1tka A:3-337 [31815]
        Other proteins in same PDB: d1tkaa2, d1tkaa3, d1tkab2, d1tkab3
        complexed with ca, n3t
      2. 2108694Domain d1tkab1: 1tka B:3-337 [31817]
        Other proteins in same PDB: d1tkaa2, d1tkaa3, d1tkab2, d1tkab3
        complexed with ca, n3t
    5. Domains for 1tkb:
      1. 2108689Domain d1tkba1: 1tkb A:3-337 [31807]
        Other proteins in same PDB: d1tkba2, d1tkba3, d1tkbb2, d1tkbb3
        complexed with ca, n1t
      2. 2108690Domain d1tkbb1: 1tkb B:3-337 [31809]
        Other proteins in same PDB: d1tkba2, d1tkba3, d1tkbb2, d1tkbb3
        complexed with ca, n1t
    6. Domains for 1tkc:
      1. 2108691Domain d1tkca1: 1tkc A:3-337 [31811]
        Other proteins in same PDB: d1tkca2, d1tkca3, d1tkcb2, d1tkcb3
        complexed with ca, m6t
      2. 2108692Domain d1tkcb1: 1tkc B:3-337 [31813]
        Other proteins in same PDB: d1tkca2, d1tkca3, d1tkcb2, d1tkcb3
        complexed with ca, m6t
    7. Domains for 1trk:
      1. 2108687Domain d1trka1: 1trk A:3-337 [31803]
        Other proteins in same PDB: d1trka2, d1trka3, d1trkb2, d1trkb3
        complexed with ca, tpp
      2. 2108688Domain d1trkb1: 1trk B:3-337 [31805]
        Other proteins in same PDB: d1trka2, d1trka3, d1trkb2, d1trkb3
        complexed with ca, tpp
  2. 2108699Escherichia coli [TaxId:562] [89656] (4 PDB entries)
    1. Domains for 1qgd:
      1. 2108706Domain d1qgda2: 1qgd A:2-332 [88368]
        Other proteins in same PDB: d1qgda1, d1qgda3, d1qgdb1, d1qgdb3
        complexed with ca, so4, tpp
      2. 2108707Domain d1qgdb2: 1qgd B:2-332 [88371]
        Other proteins in same PDB: d1qgda1, d1qgda3, d1qgdb1, d1qgdb3
        complexed with ca, so4, tpp
    2. Domains for 2r5n:
      1. 2108702Domain d2r5na2: 2r5n A:2-332 [151592]
        Other proteins in same PDB: d2r5na1, d2r5na3, d2r5na4, d2r5nb1, d2r5nb3, d2r5nb4
        automated match to d1qgda2
        complexed with ca, edo, r5p, rp5, tpp
      2. 2108703Domain d2r5nb2: 2r5n B:2-332 [151595]
        Other proteins in same PDB: d2r5na1, d2r5na3, d2r5na4, d2r5nb1, d2r5nb3, d2r5nb4
        automated match to d1qgda2
        complexed with ca, edo, r5p, rp5, tpp
    3. Domains for 2r8o:
      1. 2108700Domain d2r8oa2: 2r8o A:2-332 [151732]
        Other proteins in same PDB: d2r8oa1, d2r8oa3, d2r8ob1, d2r8ob3, d2r8ob4
        automated match to d1qgda2
        complexed with ca, edo, t5x
      2. 2108701Domain d2r8ob2: 2r8o B:2-332 [151735]
        Other proteins in same PDB: d2r8oa1, d2r8oa3, d2r8ob1, d2r8ob3, d2r8ob4
        automated match to d1qgda2
        complexed with ca, edo, t5x
    4. Domains for 2r8p:
      1. 2108704Domain d2r8pa2: 2r8p A:2-332 [151738]
        Other proteins in same PDB: d2r8pa1, d2r8pa3, d2r8pb1, d2r8pb3, d2r8pb4
        automated match to d1qgda2
        complexed with ca, edo, t6f
      2. 2108705Domain d2r8pb2: 2r8p B:2-332 [151741]
        Other proteins in same PDB: d2r8pa1, d2r8pa3, d2r8pb1, d2r8pb3, d2r8pb4
        automated match to d1qgda2
        complexed with ca, edo, t6f
  3. 2108708Leishmania mexicana mexicana [TaxId:44270] [117524] (1 PDB entry)
    Uniprot Q8MPM3
  4. 2108711Maize (Zea mays) [TaxId:4577] [88763] (1 PDB entry)

More info for Protein Transketolase (TK), PP module from c.36.1.10: TK-like PP module

Timeline for Protein Transketolase (TK), PP module from c.36.1.10: TK-like PP module: