Lineage for Protein: Acetohydroxyacid synthase catalytic subunit

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 694610Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 694611Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 694852Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module [88749] (8 proteins)
    the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology
  6. 694853Protein Acetohydroxyacid synthase catalytic subunit [88758] (2 species)

Species:

  1. 694854Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88759] (6 PDB entries)
    1. Domains for 1jsc:
      1. 694865Domain d1jsca3: 1jsc A:461-648 [67226]
        Other proteins in same PDB: d1jsca1, d1jsca2, d1jscb1, d1jscb2
      2. 694866Domain d1jscb3: 1jsc B:464-649 [67229]
        Other proteins in same PDB: d1jsca1, d1jsca2, d1jscb1, d1jscb2
        complexed with 2hp, fad, k, mg, tpp
    2. Domains for 1n0h:
      1. 694867Domain d1n0ha3: 1n0h A:461-687 [79736]
        Other proteins in same PDB: d1n0ha1, d1n0ha2, d1n0hb1, d1n0hb2
      2. 694868Domain d1n0hb3: 1n0h B:461-687 [79739]
        Other proteins in same PDB: d1n0ha1, d1n0ha2, d1n0hb1, d1n0hb2
        complexed with ayd, cie, dtt, fad, k, mg, tpp
    3. Domains for 1t9a:
      1. 694863Domain d1t9aa3: 1t9a A:461-687 [112330]
        Other proteins in same PDB: d1t9aa1, d1t9aa2, d1t9ab1, d1t9ab2
      2. 694864Domain d1t9ab3: 1t9a B:461-687 [112333]
        Other proteins in same PDB: d1t9aa1, d1t9aa2, d1t9ab1, d1t9ab2
        complexed with 1tb, fad, k, mg, p23, yf3, yf4
    4. Domains for 1t9b:
      1. 694855Domain d1t9ba3: 1t9b A:461-687 [112336]
        Other proteins in same PDB: d1t9ba1, d1t9ba2, d1t9bb1, d1t9bb2
      2. 694856Domain d1t9bb3: 1t9b B:461-687 [112339]
        Other proteins in same PDB: d1t9ba1, d1t9ba2, d1t9bb1, d1t9bb2
        complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3
    5. Domains for 1t9c:
      1. 694861Domain d1t9ca3: 1t9c A:461-687 [112342]
        Other proteins in same PDB: d1t9ca1, d1t9ca2, d1t9cb1, d1t9cb2
      2. 694862Domain d1t9cb3: 1t9c B:461-687 [112345]
        Other proteins in same PDB: d1t9ca1, d1t9ca2, d1t9cb1, d1t9cb2
        complexed with 1sm, fad, k, mg, p22, p23
    6. Domains for 1t9d:
      1. 694857Domain d1t9da3: 1t9d A:461-687 [112348]
        Other proteins in same PDB: d1t9da1, d1t9da2, d1t9db1, d1t9db2, d1t9dc1, d1t9dc2, d1t9dd1, d1t9dd2
      2. 694858Domain d1t9db3: 1t9d B:461-687 [112351]
        Other proteins in same PDB: d1t9da1, d1t9da2, d1t9db1, d1t9db2, d1t9dc1, d1t9dc2, d1t9dd1, d1t9dd2
      3. 694859Domain d1t9dc3: 1t9d C:461-687 [112354]
        Other proteins in same PDB: d1t9da1, d1t9da2, d1t9db1, d1t9db2, d1t9dc1, d1t9dc2, d1t9dd1, d1t9dd2
      4. 694860Domain d1t9dd3: 1t9d D:461-687 [112357]
        Other proteins in same PDB: d1t9da1, d1t9da2, d1t9db1, d1t9db2, d1t9dc1, d1t9dc2, d1t9dd1, d1t9dd2
        complexed with 1mm, fad, k, mg, p22, p25, yf1
  2. 694869Thale cress (Arabidopsis thaliana), chloroplast [TaxId:3702] [142208] (6 PDB entries)
    1. Domain for 1ybh:
    2. Domain for 1yhy:
    3. Domain for 1yhz:
    4. Domain for 1yi0:
    5. Domain for 1yi1:
    6. Domain for 1z8n:

More info for Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.9: Pyruvate oxidase and decarboxylase PP module

Timeline for Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.9: Pyruvate oxidase and decarboxylase PP module:

  • Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.9: Pyruvate oxidase and decarboxylase PP module first appeared in SCOP 1.65
  • Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.9: Pyruvate oxidase and decarboxylase PP module appears in SCOP 1.71
  • Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.9: Pyruvate oxidase and decarboxylase PP module appears in SCOP 1.75
  • Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.9: Pyruvate oxidase and decarboxylase PP module appears in the current release, SCOPe 2.07