Lineage for Protein: Acetohydroxyacid synthase catalytic subunit
- Root: SCOP 1.67
Class c: Alpha and beta proteins (a/b) [51349] (130 folds) 
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) 
there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module [88749] (7 proteins)
the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology
Protein Acetohydroxyacid synthase catalytic subunit [88758] (1 species)
Species:
Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88759] (2 PDB entries) - Domains for 1jsc:
Domain d1jsca3: 1jsc A:461-648 [67226]
Other proteins in same PDB: d1jsca1, d1jsca2, d1jscb1, d1jscb2
Domain d1jscb3: 1jsc B:464-649 [67229]
Other proteins in same PDB: d1jsca1, d1jsca2, d1jscb1, d1jscb2
complexed with 2hp, fad, k, mg, tpp
- Domains for 1n0h:
Domain d1n0ha3: 1n0h A:461-687 [79736]
Other proteins in same PDB: d1n0ha1, d1n0ha2, d1n0hb1, d1n0hb2
Domain d1n0hb3: 1n0h B:461-687 [79739]
Other proteins in same PDB: d1n0ha1, d1n0ha2, d1n0hb1, d1n0hb2
complexed with ayd, cie, dtt, fad, k, mg, tpp
- Domains for 1jsc:
More info for Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.9: Pyruvate oxidase and decarboxylase PP module
Timeline for Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.9: Pyruvate oxidase and decarboxylase PP module:
- Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.9: Pyruvate oxidase and decarboxylase PP module first appeared in SCOP 1.65
- Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.9: Pyruvate oxidase and decarboxylase PP module appears in SCOP 1.69
- Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.9: Pyruvate oxidase and decarboxylase PP module appears in the current release, SCOPe 2.08