Lineage for Species: Brewer's yeast (Saccharomyces), uvarum strain
- Root: SCOP 1.67
Class c: Alpha and beta proteins (a/b) [51349] (130 folds) 
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) 
there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module [88749] (7 proteins)
the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology
Protein Pyruvate decarboxylase [88750] (3 species) 
Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] [88751] (1 PDB entry)
PDB entry in Species: Brewer's yeast (Saccharomyces), uvarum strain:
- Domain(s) for 1pyd:
Domain d1pyda3: 1pyd A:361-556 [31774]
Other proteins in same PDB: d1pyda1, d1pyda2, d1pydb1, d1pydb2
Domain d1pydb3: 1pyd B:361-556 [31776]
Other proteins in same PDB: d1pyda1, d1pyda2, d1pydb1, d1pydb2
complexed with mg, tdp
More info for Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] from c.36.1.9 Pyruvate decarboxylase
Timeline for Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] from c.36.1.9 Pyruvate decarboxylase:
- Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] from c.36.1.9 Pyruvate decarboxylase first appeared in SCOP 1.65
- Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] from c.36.1.9 Pyruvate decarboxylase appears in SCOP 1.69
- Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] from c.36.1.9 Pyruvate decarboxylase appears in the current release, SCOPe 2.08, called Species Brewer's yeast (Saccharomyces uvarum) [TaxId:230603] from c.36.1.9 Pyruvate decarboxylase