Lineage for Species: Human (Homo sapiens)

  1. Root: SCOP 1.69
  2. 473232Class c: Alpha and beta proteins (a/b) [51349] (136 folds)
  3. 483377Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 483378Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 483487Family c.36.1.7: Branched-chain alpha-keto acid dehydrogenase Pyr module [88741] (3 proteins)
    parent family to TK and PFOR
    heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module
  6. 483491Protein Branched-chain alpha-keto acid dehydrogenase, Pyr module [88742] (2 species)
  7. 483492Species Human (Homo sapiens) [TaxId:9606] [88743] (8 PDB entries)

PDB entries in Species: Human (Homo sapiens):

  1. Domain(s) for 1dtw:
  2. Domain(s) for 1ols:
  3. Domain(s) for 1olu:
  4. Domain(s) for 1olx:
  5. Domain(s) for 1v11:
  6. Domain(s) for 1v16:
  7. Domain(s) for 1v1m:
  8. Domain(s) for 1v1r:

More info for Species Human (Homo sapiens) [TaxId:9606] from c.36.1.7 Branched-chain alpha-keto acid dehydrogenase, Pyr module

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.36.1.7 Branched-chain alpha-keto acid dehydrogenase, Pyr module: