Lineage for Species: Escherichia coli [TaxId: 562]

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2445862Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 2445863Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 2446007Family c.36.1.6: TK-like Pyr module [88735] (2 protein domains)
    different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain
  6. 2446008Protein Pyruvate dehydrogenase E1 component, Pyr module [88739] (1 species)
    E1A and E1B fused together in a single-chain protein
  7. 2446009Species Escherichia coli [TaxId:562] [88740] (6 PDB entries)

PDB entries in Species: Escherichia coli [TaxId: 562]:

  1. Domain(s) for 1l8a:
    1. 2446010Domain d1l8aa2: 1l8a A:471-700 [73678]
      Other proteins in same PDB: d1l8aa1, d1l8aa3, d1l8ab1, d1l8ab3
      complexed with mg, tdp
    2. 2446011Domain d1l8ab2: 1l8a B:471-700 [73681]
      Other proteins in same PDB: d1l8aa1, d1l8aa3, d1l8ab1, d1l8ab3
      complexed with mg, tdp
  2. Domain(s) for 1rp7:
    1. 2446014Domain d1rp7a1: 1rp7 A:471-700 [97702]
      Other proteins in same PDB: d1rp7a2, d1rp7a3, d1rp7b2, d1rp7b3
      complexed with mg, tzd
    2. 2446015Domain d1rp7b1: 1rp7 B:471-700 [97705]
      Other proteins in same PDB: d1rp7a2, d1rp7a3, d1rp7b2, d1rp7b3
      complexed with mg, tzd
  3. Domain(s) for 2g25:
    1. 2446018Domain d2g25a1: 2g25 A:471-700 [134523]
      Other proteins in same PDB: d2g25a2, d2g25a3, d2g25b2, d2g25b3
      automated match to d1l8aa2
      complexed with mg, po4, tdk
    2. 2446019Domain d2g25b1: 2g25 B:471-700 [134526]
      Other proteins in same PDB: d2g25a2, d2g25a3, d2g25b2, d2g25b3
      automated match to d1l8aa2
      complexed with mg, po4, tdk
  4. Domain(s) for 2g28:
    1. 2446012Domain d2g28a1: 2g28 A:471-700 [134529]
      Other proteins in same PDB: d2g28a2, d2g28a3, d2g28b2, d2g28b3
      automated match to d1l8aa2
      complexed with mg, tdk
    2. 2446013Domain d2g28b1: 2g28 B:471-700 [134532]
      Other proteins in same PDB: d2g28a2, d2g28a3, d2g28b2, d2g28b3
      automated match to d1l8aa2
      complexed with mg, tdk
  5. Domain(s) for 2g67:
    1. 2446020Domain d2g67a1: 2g67 A:471-700 [134695]
      Other proteins in same PDB: d2g67a2, d2g67a3, d2g67b2, d2g67b3
      automated match to d1l8aa2
    2. 2446021Domain d2g67b1: 2g67 B:471-700 [134698]
      Other proteins in same PDB: d2g67a2, d2g67a3, d2g67b2, d2g67b3
      automated match to d1l8aa2
  6. Domain(s) for 2iea:
    1. 2446016Domain d2ieaa1: 2iea A:471-700 [137294]
      Other proteins in same PDB: d2ieaa2, d2ieaa3, d2ieab2, d2ieab3
      automated match to d1l8aa2
      complexed with mg, tdp
    2. 2446017Domain d2ieab1: 2iea B:471-700 [137297]
      Other proteins in same PDB: d2ieaa2, d2ieaa3, d2ieab2, d2ieab3
      automated match to d1l8aa2
      complexed with mg, tdp

More info for Species Escherichia coli [TaxId:562] from c.36.1.6 Pyruvate dehydrogenase E1 component, Pyr module

Timeline for Species Escherichia coli [TaxId:562] from c.36.1.6 Pyruvate dehydrogenase E1 component, Pyr module: