Lineage for Protein: Pyruvate oxidase

  1. Root: SCOP 1.75
  2. 814173Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 828800Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 828801Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 828802Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module [88724] (8 proteins)
    the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpha/beta domain of Rossmann-like topology
  6. 828923Protein Pyruvate oxidase [88729] (2 species)

Species:

  1. 828924Aerococcus viridans [TaxId:1377] [142203] (4 PDB entries)
    1. Domain for 1v5e:
    2. Domain for 1v5f:
    3. Domain for 1v5g:
    4. Domain for 2dji:
  2. 828929Lactobacillus plantarum [TaxId:1590] [88730] (7 PDB entries)
    1. Domains for 1pow:
      1. 828942Domain d1powa2: 1pow A:9-182 [31797]
        Other proteins in same PDB: d1powa1, d1powa3, d1powb1, d1powb3
      2. 828943Domain d1powb2: 1pow B:9-182 [31799]
        Other proteins in same PDB: d1powa1, d1powa3, d1powb1, d1powb3
        complexed with fad, mg, tpp
    2. Domains for 1pox:
      1. 828936Domain d1poxa2: 1pox A:9-182 [31793]
        Other proteins in same PDB: d1poxa1, d1poxa3, d1poxb1, d1poxb3
      2. 828937Domain d1poxb2: 1pox B:9-182 [31795]
        Other proteins in same PDB: d1poxa1, d1poxa3, d1poxb1, d1poxb3
        complexed with fad, gol, mg, na, tpp; mutant
    3. Domains for 2ez4:
      1. 828934Domain d2ez4a2: 2ez4 A:9-182 [132611]
        Other proteins in same PDB: d2ez4a1, d2ez4a3, d2ez4b1, d2ez4b3
        automatically matched to d1powa2
        complexed with fad, mg, na, po4, tpp; mutant
      2. 828935Domain d2ez4b2: 2ez4 B:9-182 [132614]
        Other proteins in same PDB: d2ez4a1, d2ez4a3, d2ez4b1, d2ez4b3
        automatically matched to d1powa2
        complexed with fad, mg, na, po4, tpp; mutant
    4. Domains for 2ez8:
      1. 828932Domain d2ez8a2: 2ez8 A:9-182 [132622]
        Other proteins in same PDB: d2ez8a1, d2ez8a3, d2ez8b1, d2ez8b3
        automatically matched to d1powa2
        complexed with fad, mg, na, pyr, tdl; mutant
      2. 828933Domain d2ez8b2: 2ez8 B:9-182 [132625]
        Other proteins in same PDB: d2ez8a1, d2ez8a3, d2ez8b1, d2ez8b3
        automatically matched to d1powa2
        complexed with fad, mg, na, pyr, tdl; mutant
    5. Domains for 2ez9:
      1. 828930Domain d2ez9a2: 2ez9 A:9-182 [132628]
        Other proteins in same PDB: d2ez9a1, d2ez9a3, d2ez9b1, d2ez9b3
        automatically matched to d1powa2
        complexed with fad, mg, na, tdk; mutant
      2. 828931Domain d2ez9b2: 2ez9 B:9-182 [132631]
        Other proteins in same PDB: d2ez9a1, d2ez9a3, d2ez9b1, d2ez9b3
        automatically matched to d1powa2
        complexed with fad, mg, na, tdk; mutant
    6. Domains for 2ezt:
      1. 828940Domain d2ezta2: 2ezt A:9-182 [132634]
        Other proteins in same PDB: d2ezta1, d2ezta3, d2eztb1, d2eztb3
        automatically matched to d1powa2
        complexed with fad, mg, na, po4, pyr, tdm; mutant
      2. 828941Domain d2eztb2: 2ezt B:9-182 [132637]
        Other proteins in same PDB: d2ezta1, d2ezta3, d2eztb1, d2eztb3
        automatically matched to d1powa2
        complexed with fad, mg, na, po4, pyr, tdm; mutant
    7. Domains for 2ezu:
      1. 828938Domain d2ezua2: 2ezu A:9-182 [132640]
        Other proteins in same PDB: d2ezua1, d2ezua3, d2ezub1, d2ezub3
        automatically matched to d1powa2
        complexed with fad, htl, mg, na, pyr; mutant
      2. 828939Domain d2ezub2: 2ezu B:9-182 [132643]
        Other proteins in same PDB: d2ezua1, d2ezua3, d2ezub1, d2ezub3
        automatically matched to d1powa2
        complexed with fad, htl, mg, na, pyr; mutant

More info for Protein Pyruvate oxidase from c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module

Timeline for Protein Pyruvate oxidase from c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module: