SCOPe 2.08: Protein: Methylmalonyl-CoA mutase alpha subunit, domain 1

Lineage for Protein: Methylmalonyl-CoA mutase alpha subunit, domain 1

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
the first seven superfamilies have similar phosphate-binding sites

Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes [51703] (4 families)
Family c.1.19.1: Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain [51704] (2 proteins)
the subunits are clearly related but only one (alpha) is active
automatically mapped to Pfam PF01642
Protein Methylmalonyl-CoA mutase alpha subunit, domain 1 [88709] (1 species)

Species:

Propionibacterium freudenreichii, subsp. shermanii [TaxId:1744] [88710] (8 PDB entries)
1. Domains for 1e1c:
  1. Domain d1e1ca1: 1e1c A:2-560 [29636]
    Other proteins in same PDB: d1e1ca2, d1e1cb1, d1e1cb2, d1e1cc2, d1e1cd1, d1e1cd2
    complexed with b12, dca; mutant
  2. Domain d1e1cc1: 1e1c C:2-560 [29638]
    Other proteins in same PDB: d1e1ca2, d1e1cb1, d1e1cb2, d1e1cc2, d1e1cd1, d1e1cd2
    complexed with b12, dca; mutant
2. Domains for 1req:
  1. Domain d1reqa1: 1req A:2-560 [29620]
    Other proteins in same PDB: d1reqa2, d1reqb1, d1reqb2, d1reqc2, d1reqd1, d1reqd2
    complexed with b12, dca, gol
  2. Domain d1reqc1: 1req C:2-560 [29622]
    Other proteins in same PDB: d1reqa2, d1reqb1, d1reqb2, d1reqc2, d1reqd1, d1reqd2
    complexed with b12, dca, gol
3. Domains for 2req:
  1. Domain d2reqa1: 2req A:4-560 [29640]
    Other proteins in same PDB: d2reqa2, d2reqb1, d2reqb2, d2reqc2, d2reqd1, d2reqd2
    complexed with b12, coa
  2. Domain d2reqc1: 2req C:4-560 [29642]
    Other proteins in same PDB: d2reqa2, d2reqb1, d2reqb2, d2reqc2, d2reqd1, d2reqd2
    complexed with b12, coa
4. Domain for 3req:
  - Domain d3reqa1: 3req A:4-560 [29644]
    Other proteins in same PDB: d3reqa2, d3reqb1, d3reqb2
    complexed with adn, b12
5. Domains for 4req:
  1. Domain d4reqa1: 4req A:3-560 [29628]
    Other proteins in same PDB: d4reqa2, d4reqb1, d4reqb2, d4reqc2, d4reqd1, d4reqd2
    complexed with 5ad, b12, gol, mca, sca
  2. Domain d4reqc1: 4req C:3-560 [29630]
    Other proteins in same PDB: d4reqa2, d4reqb1, d4reqb2, d4reqc2, d4reqd1, d4reqd2
    complexed with 5ad, b12, gol, mca, sca
6. Domains for 5req:
  1. Domain d5reqa1: 5req A:4-560 [29632]
    Other proteins in same PDB: d5reqa2, d5reqb1, d5reqb2, d5reqc2, d5reqd1, d5reqd2
    complexed with b12, gol, mcd, scd; mutant
  2. Domain d5reqc1: 5req C:4-560 [29634]
    Other proteins in same PDB: d5reqa2, d5reqb1, d5reqb2, d5reqc2, d5reqd1, d5reqd2
    complexed with b12, gol, mcd, scd; mutant
7. Domains for 6req:
  1. Domain d6reqa1: 6req A:2-560 [29624]
    Other proteins in same PDB: d6reqa2, d6reqb1, d6reqb2, d6reqc2, d6reqd1, d6reqd2
    complexed with 3cp, b12, gol
  2. Domain d6reqc1: 6req C:2-560 [29626]
    Other proteins in same PDB: d6reqa2, d6reqb1, d6reqb2, d6reqc2, d6reqd1, d6reqd2
    complexed with 3cp, b12, gol
8. Domains for 7req:
  1. Domain d7reqa1: 7req A:4-560 [29616]
    Other proteins in same PDB: d7reqa2, d7reqb1, d7reqb2, d7reqc2, d7reqd1, d7reqd2
    complexed with 2cp, b12, gol
  2. Domain d7reqc1: 7req C:4-560 [29618]
    Other proteins in same PDB: d7reqa2, d7reqb1, d7reqb2, d7reqc2, d7reqd1, d7reqd2
    complexed with 2cp, b12, gol

More info for Protein Methylmalonyl-CoA mutase alpha subunit, domain 1 from c.1.19.1: Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain

Timeline for Protein Methylmalonyl-CoA mutase alpha subunit, domain 1 from c.1.19.1: Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain:

Protein Methylmalonyl-CoA mutase alpha subunit, domain 1 from c.1.19.1: Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain first appeared in SCOP 1.65
Protein Methylmalonyl-CoA mutase alpha subunit, domain 1 from c.1.19.1: Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain appears in SCOPe 2.07