SCOP 1.65: Family a.8.3.1: alpha-mannosidase, domain 2

Lineage for Family a.8.3.1: alpha-mannosidase, domain 2

1. Root: SCOP 1.65

2. Class a: All alpha proteins [46456] (179 folds)

3. Fold a.8: immunoglobulin/albumin-binding domain-like [46996] (3 superfamilies)
   3 helices; bundle, closed, left-handed twist; up-and-down; mirror topology to the spectrin-like fold

4. Superfamily a.8.3: Families 57/38 glycoside transferase middle domain [88688] (2 families)

5. Family a.8.3.1: alpha-mannosidase, domain 2 [88693] (2 proteins)
   family 38 glycoside hydrolase; overall domain organisation is similar to that of the 4-alpha-glucanotransferase family

Proteins:

1. Golgi alpha-mannosidase II [88694] (1 species)

   • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [88695] (3 PDB entries)

2. Lysosomal alpha-mannosidase [89016] (1 species)
   the single-chain precursor is processed into 5 peptides; heavily glycosylated

   • Species Cow (Bos taurus) [TaxId:9913] [89017] (1 PDB entry)

More info for Family a.8.3.1: alpha-mannosidase, domain 2

Timeline for Family a.8.3.1: alpha-mannosidase, domain 2:

• Family a.8.3.1: alpha-mannosidase, domain 2 is new in SCOP 1.65
  
• Family a.8.3.1: alpha-mannosidase, domain 2 appears in SCOP 1.67
  
• Family a.8.3.1: alpha-mannosidase, domain 2 appears in the current release, SCOPe 2.08