SCOP 1.71: Family b.30.5.6: alpha-mannosidase, C-terminal domain

Lineage for Family b.30.5.6: alpha-mannosidase, C-terminal domain

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.30: Supersandwich [49993] (3 superfamilies)
   sandwich; 18 strands in 2 sheets

4. Superfamily b.30.5: Galactose mutarotase-like [74650] (11 families)
   probable carbohydrate-binding domain in enzymes acting on sugars

5. Family b.30.5.6: alpha-mannosidase, C-terminal domain [88656] (2 proteins)
   family 38 glycoside hydrolase; overall domain organization is similar to that of the 4-alpha-glucanotransferase family
   the supersandwich domain is elaborated with additional beta-strands and beta-sandwich subdomains

Proteins:

1. Golgi alpha-mannosidase II [88657] (1 species)

   • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [88658] (9 PDB entries)

2. Lysosomal alpha-mannosidase [89289] (1 species)
   the single-chain precursor is processed into 5 peptides; heavily glycosylated

   • Species Cow (Bos taurus) [TaxId:9913] [89290] (1 PDB entry)

More info for Family b.30.5.6: alpha-mannosidase, C-terminal domain

Timeline for Family b.30.5.6: alpha-mannosidase, C-terminal domain:

• Family b.30.5.6: alpha-mannosidase, C-terminal domain first appeared in SCOP 1.65
  
• Family b.30.5.6: alpha-mannosidase, C-terminal domain appears in SCOP 1.69
  
• Family b.30.5.6: alpha-mannosidase, C-terminal domain appears in SCOP 1.73
  
• Family b.30.5.6: alpha-mannosidase, C-terminal domain appears in the current release, SCOPe 2.08