Lineage for Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4)

  1. Root: SCOP 1.65
  2. 287094Class b: All beta proteins [48724] (126 folds)
  3. 304390Fold b.121: Nucleoplasmin-like/VP (viral coat and capsid proteins) [88632] (7 superfamilies)
    sandwich; 8 strands in 2 sheets; jelly-roll; some members can have additional 1-2 strands
    characteristic interaction between the domains of this fold allows the formation of five-fold and pseudo six-fold assemblies
  4. 304471Superfamily b.121.4: Positive stranded ssRNA viruses [88633] (7 families) (S)
  5. 304472Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4) [88634] (9 proteins)
    the order of the chains N-VP0-VP3-VP1-C is as in the polyprotein; VP0 is cleaved later upon capsid assembly to VP4 and VP2
    there is a different order in the shuffled genome of insect picorna-like proteins (Cricket paralysis virus)

Proteins:

  1. 304473Aphthovirus (Foot-and-mouth desease virus) coat proteins [49659] (1 species)
  2. 304487Bovine enterovirus coat proteins [49676] (1 species)
  3. 304492Human enterovirus B coat proteins [88635] (4 species)
    1. 304493Species Human coxsackievirus A9 [TaxId:12067] [49683] (1 PDB entry)
    2. 304497Species Human coxsackievirus B3 [TaxId:12072] [49681] (1 PDB entry)
    3. 304501Species Human echovirus 1 [TaxId:46633] [49685] (1 PDB entry)
    4. 304505Species Human echovirus 11 [TaxId:12078] [74890] (1 PDB entry)
  4. 304509Insect picorna-like virus coat proteins [49654] (1 species)
    different genetic order of VP segments due to extensive genome shuffling
  5. 304514Mengo encephalomyocarditis virus coat proteins [49678] (1 species)
  6. 304522Poliovirus coat proteins [49666] (3 species)
    1. 304523Species Poliovirus type 1, strain Mahoney [TaxId:12080] [49667] (11 PDB entries)
    2. 304557Species Poliovirus type 2, strain Lansing [TaxId:12083] [49668] (1 PDB entry)
    3. 304561Species Poliovirus type 3, strain Sabin [TaxId:12086] [49669] (7 PDB entries)
  7. 304583Rhinovirus coat proteins [49670] (5 species)
    1. 304584Species Human rhinovirus A 16 (HRV-16) [49672] (6 PDB entries)
    2. 304603Species Human rhinovirus A 1A (HRV-1A) [TaxId:12134] [49673] (4 PDB entries)
    3. 304616Species Human rhinovirus A 2 (HRV-2) [TaxId:12130] [49674] (1 PDB entry)
    4. 304620Species Human rhinovirus B 14 (HRV-14) [TaxId:12131] [49671] (28 PDB entries)
    5. 304705Species Human rhinovirus B 3 (HRV-3) [49675] (1 PDB entry)
  8. 304709Swine vesicular disease virus coat proteins [89225] (1 species)
  9. 304714Theilovirus capsid proteins [49686] (1 species)

More info for Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4)

Timeline for Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4):