Lineage for Fold b.121: Nucleoplasmin-like/VP (viral coat and capsid proteins)

  1. Root: SCOPe 2.06
  2. 2021373Class b: All beta proteins [48724] (177 folds)
  3. 2086376Fold b.121: Nucleoplasmin-like/VP (viral coat and capsid proteins) [88632] (7 superfamilies)
    sandwich; 8 strands in 2 sheets; jelly-roll; some members can have additional 1-2 strands
    characteristic interaction between the domains of this fold allows the formation of five-fold and pseudo six-fold assemblies

Superfamilies:

  1. 2086377b.121.1: PHM/PNGase F [49742] (2 families) (S)
    members of this superfamily bind peptide substrates
    duplication: consists of two domains of this fold packed together like the adjacent nucleoplasmin subunits
  2. 2086428b.121.2: Group II dsDNA viruses VP [49749] (4 families) (S)
    duplication: consists of two domains of this fold packed together like the nucleoplasmin subunits
    trimeric; in the trimers, the domains are arranged around pseudo six-fold axis
  3. 2086514b.121.3: Nucleoplasmin-like core domain [69203] (2 families) (S)
    oligomerizes into a pentameric ring structure
  4. 2086604b.121.4: Positive stranded ssRNA viruses [88633] (10 families) (S)
  5. 2087350b.121.5: ssDNA viruses [88645] (3 families) (S)
  6. 2087547b.121.6: Group I dsDNA viruses [88648] (2 families) (S)
  7. 2087964b.121.7: Satellite viruses [88650] (1 family) (S)

More info for Fold b.121: Nucleoplasmin-like/VP (viral coat and capsid proteins)

Timeline for Fold b.121: Nucleoplasmin-like/VP (viral coat and capsid proteins):