Lineage for Protein: Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 781542Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 781543Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 783929Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)
  6. 785963Protein Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma [88589] (5 species)

Species:

  1. 785964Guinea pig (Cavia porcellus) [TaxId:10141] [49123] (1 PDB entry)
  2. 785966Human (Homo sapiens) [TaxId:9606] [88590] (28 PDB entries)
    Uniprot P01857 #118-327
    Uniprot P01857 118-327 # GC1_HUMAN Ig gamma-1 chain C region
    Uniprot P01857 #118-327 ! Uniprot P01857 118-327 # GC1_HUMAN Ig gamma-1 chain C region
    1. Domain for 1adq:
    2. Domains for 1dn2:
      1. 785972Domain d1dn2a2: 1dn2 A:342-443 [21513]
        Other proteins in same PDB: d1dn2a1, d1dn2b1
        part of a Fc
      2. 785973Domain d1dn2b2: 1dn2 B:342-443 [21515]
        Other proteins in same PDB: d1dn2a1, d1dn2b1
        part of a Fc
        complexed with fuc, gal, man, nag, nh2
    3. Domains for 1e4k:
      1. 786011Domain d1e4ka2: 1e4k A:342-444 [21527]
        Other proteins in same PDB: d1e4ka1, d1e4kb1, d1e4kc1, d1e4kc2
        part of a Fc
      2. 786012Domain d1e4kb2: 1e4k B:342-444 [21529]
        Other proteins in same PDB: d1e4ka1, d1e4kb1, d1e4kc1, d1e4kc2
        part of a Fc
        complexed with fuc, gal, man, nag
    4. Domains for 1fc1:
      1. 785988Domain d1fc1a2: 1fc1 A:342-444 [21521]
        Other proteins in same PDB: d1fc1a1, d1fc1b1
        part of a Fc
      2. 785989Domain d1fc1b2: 1fc1 B:342-444 [21523]
        Other proteins in same PDB: d1fc1a1, d1fc1b1
        part of a Fc
        complexed with fuc, gal, man, nag
    5. Domain for 1fc2:
    6. Domains for 1fcc:
      1. 786007Domain d1fcca2: 1fcc A:342-443 [21525]
        Other proteins in same PDB: d1fcca1, d1fccb1, d1fccc_, d1fccd_
        part of a Fc
      2. 786008Domain d1fccb2: 1fcc B:342-443 [118452]
        Other proteins in same PDB: d1fcca1, d1fccb1, d1fccc_, d1fccd_
        duplicate of 1FCC A:342-443
    7. Domain for 1frt:
    8. Domains for 1h3t:
      1. 785982Domain d1h3ta2: 1h3t A:342-445 [76654]
        Other proteins in same PDB: d1h3ta1, d1h3tb1
        part of a Fc
      2. 785983Domain d1h3tb2: 1h3t B:342-444 [76656]
        Other proteins in same PDB: d1h3ta1, d1h3tb1
        part of a Fc
        complexed with afl, bma, nag
    9. Domains for 1h3u:
      1. 785977Domain d1h3ua2: 1h3u A:342-445 [76658]
        Other proteins in same PDB: d1h3ua1, d1h3ub1
        part of a Fc
      2. 785978Domain d1h3ub2: 1h3u B:342-444 [76660]
        Other proteins in same PDB: d1h3ua1, d1h3ub1
        part of a Fc
        complexed with afl, bma, man, nag
    10. Domains for 1h3v:
      1. 786005Domain d1h3va2: 1h3v A:342-445 [76662]
        Other proteins in same PDB: d1h3va1, d1h3vb1
        part of a Fc
      2. 786006Domain d1h3vb2: 1h3v B:342-444 [76664]
        Other proteins in same PDB: d1h3va1, d1h3vb1
        part of a Fc
        part of a Fc
        complexed with afl, bma, gal, nag
    11. Domain for 1h3w:
    12. Domains for 1h3x:
      1. 785986Domain d1h3xa2: 1h3x A:342-445 [90603]
        Other proteins in same PDB: d1h3xa1, d1h3xb1
        part of a Fc
      2. 785987Domain d1h3xb2: 1h3x B:342-444 [90605]
        Other proteins in same PDB: d1h3xa1, d1h3xb1
        part of a Fc
        complexed with afl, bma, man, nag, ndg
    13. Domains for 1h3y:
      1. 786014Domain d1h3ya2: 1h3y A:342-443 [76668]
        Other proteins in same PDB: d1h3ya1, d1h3yb1
        part of a Fc
      2. 786015Domain d1h3yb2: 1h3y B:342-443 [76670]
        Other proteins in same PDB: d1h3ya1, d1h3yb1
        part of a Fc
        complexed with afl, bma, gla, man, nag, ndg
    14. Domains for 1hzh:
      1. 785984Domain d1hzhh4: 1hzh H:360-478 [61440]
        Other proteins in same PDB: d1hzhh1, d1hzhh2, d1hzhh3, d1hzhk1, d1hzhk2, d1hzhk3, d1hzhl1, d1hzhl2, d1hzhm1, d1hzhm2
        part of intact IgG B12 antibody
      2. 785985Domain d1hzhk4: 1hzh K:360-475 [61444]
        Other proteins in same PDB: d1hzhh1, d1hzhh2, d1hzhh3, d1hzhk1, d1hzhk2, d1hzhk3, d1hzhl1, d1hzhl2, d1hzhm1, d1hzhm2
        part of intact IgG B12 antibody
        complexed with fuc, gal, man, nag
    15. Domain for 1l6x:
    16. Domain for 1mco:
    17. Domains for 1oqo:
      1. 785979Domain d1oqoa2: 1oqo A:342-444 [87314]
        Other proteins in same PDB: d1oqoa1, d1oqob1, d1oqoc_, d1oqod_
        part of a Fc
      2. 785980Domain d1oqob2: 1oqo B:342-443 [87316]
        Other proteins in same PDB: d1oqoa1, d1oqob1, d1oqoc_, d1oqod_
        part of a Fc
        complexed with fuc, man, nag
    18. Domains for 1oqx:
      1. 785991Domain d1oqxa2: 1oqx A:342-445 [87326]
        Other proteins in same PDB: d1oqxa1, d1oqxb1, d1oqxc_, d1oqxd_
        part of a Fc
      2. 785992Domain d1oqxb2: 1oqx B:342-444 [87328]
        Other proteins in same PDB: d1oqxa1, d1oqxb1, d1oqxc_, d1oqxd_
        part of a Fc
        part of a Fc
        complexed with fuc, man, nag
    19. Domains for 1t83:
      1. 785994Domain d1t83a2: 1t83 A:342-443 [106644]
        Other proteins in same PDB: d1t83a1, d1t83b1, d1t83c1, d1t83c2
      2. 785995Domain d1t83b2: 1t83 B:342-443 [106646]
        Other proteins in same PDB: d1t83a1, d1t83b1, d1t83c1, d1t83c2
        complexed with fuc, gal, hg2, man, nag
    20. Domains for 1t89:
      1. 786009Domain d1t89a2: 1t89 A:342-443 [106658]
        Other proteins in same PDB: d1t89a1, d1t89b1, d1t89c1, d1t89c2
      2. 786010Domain d1t89b2: 1t89 B:342-443 [106660]
        Other proteins in same PDB: d1t89a1, d1t89b1, d1t89c1, d1t89c2
        complexed with fuc, gal, man, nag
    21. Domains for 1za6:
      1. 785999Domain d1za6b3: 1za6 B:239-344 [124808]
        Other proteins in same PDB: d1za6b1, d1za6b2, d1za6d1, d1za6d2, d1za6f1, d1za6f2, d1za6h1, d1za6h2
        automatically matched to d1hzhh4
      2. 786000Domain d1za6d3: 1za6 D:239-344 [124811]
        Other proteins in same PDB: d1za6b1, d1za6b2, d1za6d1, d1za6d2, d1za6f1, d1za6f2, d1za6h1, d1za6h2
        automatically matched to d1hzhh4
      3. 786001Domain d1za6f3: 1za6 F:239-344 [124814]
        Other proteins in same PDB: d1za6b1, d1za6b2, d1za6d1, d1za6d2, d1za6f1, d1za6f2, d1za6h1, d1za6h2
        automatically matched to d1hzhh4
      4. 786002Domain d1za6h3: 1za6 H:239-344 [124817]
        Other proteins in same PDB: d1za6b1, d1za6b2, d1za6d1, d1za6d2, d1za6f1, d1za6f2, d1za6h1, d1za6h2
        automatically matched to d1hzhh4
    22. Domains for 2dtq:
      1. 785968Domain d2dtqa2: 2dtq A:340-444 [131726]
        Other proteins in same PDB: d2dtqa1, d2dtqb1
        automatically matched to d1hzhh4
        complexed with bma, fuc, man, nag
      2. 785969Domain d2dtqb2: 2dtq B:340-444 [131728]
        Other proteins in same PDB: d2dtqa1, d2dtqb1
        automatically matched to d1hzhh4
        complexed with bma, fuc, man, nag
    23. Domains for 2dts:
      1. 785970Domain d2dtsa2: 2dts A:340-444 [131730]
        Other proteins in same PDB: d2dtsa1, d2dtsb1
        automatically matched to d1hzhh4
        complexed with bma, man, nag
      2. 785971Domain d2dtsb2: 2dts B:340-444 [131732]
        Other proteins in same PDB: d2dtsa1, d2dtsb1
        automatically matched to d1hzhh4
        complexed with bma, man, nag
    24. Domains for 2gj7:
      1. 786003Domain d2gj7a2: 2gj7 A:340-443 [135265]
        Other proteins in same PDB: d2gj7a1, d2gj7b1, d2gj7e1, d2gj7f1
        automatically matched to d1hzhh4
        complexed with bma, fuc, gal, man, nag
      2. 786004Domain d2gj7b2: 2gj7 B:340-443 [135267]
        Other proteins in same PDB: d2gj7a1, d2gj7b1, d2gj7e1, d2gj7f1
        automatically matched to d1hzhh4
        complexed with bma, fuc, gal, man, nag
    25. Domains for 2iwg:
      1. 785975Domain d2iwga2: 2iwg A:340-443 [137753]
        Other proteins in same PDB: d2iwga1, d2iwgb1, d2iwgd1, d2iwge1
        automatically matched to d1hzhh4
        complexed with fu4, gal, man, nag
      2. 785976Domain d2iwgd2: 2iwg D:340-443 [137755]
        Other proteins in same PDB: d2iwga1, d2iwgb1, d2iwgd1, d2iwge1
        automatically matched to d1hzhh4
        complexed with fu4, gal, man, nag
    26. Domains for 2j6e:
      1. 785996Domain d2j6ea2: 2j6e A:340-445 [138081]
        Other proteins in same PDB: d2j6ea1, d2j6eb1, d2j6eh1, d2j6eh2, d2j6ei1, d2j6ei2, d2j6el1, d2j6el2, d2j6em1, d2j6em2
        automatically matched to d1hzhh4
        complexed with act, bma, cac, cd, ful, gal, man, mpd, nag, ndg, zn
      2. 785997Domain d2j6eb2: 2j6e B:340-445 [138083]
        Other proteins in same PDB: d2j6ea1, d2j6eb1, d2j6eh1, d2j6eh2, d2j6ei1, d2j6ei2, d2j6el1, d2j6el2, d2j6em1, d2j6em2
        automatically matched to d1hzhh4
        complexed with act, bma, cac, cd, ful, gal, man, mpd, nag, ndg, zn
    27. Domain for 2ql1:
    28. Domain for 3c2s:
  3. 786017Mouse (Mus musculus) [TaxId:10090] [88591] (2 PDB entries)
    1. Domains for 1cqk:
      1. 786018Domain d1cqka_: 1cqk A: [21547]
        CH-gamma-3 domain only from antibody MAK33
      2. 786019Domain d1cqkb_: 1cqk B: [21548]
        CH-gamma-3 domain only from antibody MAK33
        mutant
    2. Domains for 1igy:
      1. 786020Domain d1igyb4: 1igy B:363-474 [20877]
        Other proteins in same PDB: d1igya1, d1igya2, d1igyb1, d1igyb2, d1igyb3, d1igyc1, d1igyc2, d1igyd1, d1igyd2, d1igyd3
        part of intact IgG1 antibody Mab61.1.3
      2. 786021Domain d1igyd4: 1igy D:363-474 [20881]
        Other proteins in same PDB: d1igya1, d1igya2, d1igyb1, d1igyb2, d1igyb3, d1igyc1, d1igyc2, d1igyd1, d1igyd2, d1igyd3
        part of intact IgG1 antibody Mab61.1.3
        complexed with fuc, gal, man, nag
  4. 786022Mouse (Mus musculus), gamma2 [TaxId:10090] [88592] (1 PDB entry)
  5. 786025Rat (Rattus norvegicus) [TaxId:10116] [88593] (2 PDB entries)
    1. Domains for 1i1a:
      1. 786028Domain d1i1ac2: 1i1a C:342-443 [21541]
        Other proteins in same PDB: d1i1aa1, d1i1aa2, d1i1ab_, d1i1ac1, d1i1ad1
        part of a Fc
      2. 786029Domain d1i1ad2: 1i1a D:342-443 [21543]
        Other proteins in same PDB: d1i1aa1, d1i1aa2, d1i1ab_, d1i1ac1, d1i1ad1
        part of a Fc
        complexed with cys, fuc, man, nag; mutant
    2. Domains for 1i1c:
      1. 786026Domain d1i1ca2: 1i1c A:342-443 [21537]
        Other proteins in same PDB: d1i1ca1, d1i1cb1
        part of a Fc
      2. 786027Domain d1i1cb2: 1i1c B:342-443 [21539]
        Other proteins in same PDB: d1i1ca1, d1i1cb1
        part of a Fc
        complexed with fuc, man, nag; mutant

More info for Protein Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma from b.1.1.2: C1 set domains (antibody constant domain-like)

Timeline for Protein Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma from b.1.1.2: C1 set domains (antibody constant domain-like):

  • Protein Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma from b.1.1.2: C1 set domains (antibody constant domain-like) first appeared in SCOP 1.65
  • Protein Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma from b.1.1.2: C1 set domains (antibody constant domain-like) appears in SCOP 1.73
  • Protein Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma from b.1.1.2: C1 set domains (antibody constant domain-like) appears in SCOPe 2.01
  • Protein Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma from b.1.1.2: C1 set domains (antibody constant domain-like) appears in the current release, SCOPe 2.07