SCOPe 2.01: Protein: Camelid IG heavy chain variable domain, VHh

Lineage for Protein: Camelid IG heavy chain variable domain, VHh

Root: SCOPe 2.01
Class b: All beta proteins [48724] (174 folds)
Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
sandwich; 7 strands in 2 sheets; greek-key
some members of the fold have additional strands
Superfamily b.1.1: Immunoglobulin [48726] (5 families)
Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
Protein Camelid IG heavy chain variable domain, VHh [88563] (3 species)

Species:

Camel (Camelus dromedarius) [TaxId:9838] [88564] (19 PDB entries)
SQ NA # camelid antibody
1. Domains for 1bzq:
  1. Domain d1bzqk_: 1bzq K: [20507]
    Other proteins in same PDB: d1bzqa_, d1bzqb_, d1bzqc_, d1bzqd_
    anti-RNase A VHh domain
    protein/RNA complex; complexed with po4
  2. Domain d1bzql_: 1bzq L: [20508]
    Other proteins in same PDB: d1bzqa_, d1bzqb_, d1bzqc_, d1bzqd_
    anti-RNase A VHh domain
    protein/RNA complex; complexed with po4
  3. Domain d1bzqm_: 1bzq M: [20509]
    Other proteins in same PDB: d1bzqa_, d1bzqb_, d1bzqc_, d1bzqd_
    anti-RNase A VHh domain
    protein/RNA complex; complexed with po4
  4. Domain d1bzqn_: 1bzq N: [20510]
    Other proteins in same PDB: d1bzqa_, d1bzqb_, d1bzqc_, d1bzqd_
    anti-RNase A VHh domain
    protein/RNA complex; complexed with po4
2. Domains for 1f2x:
  1. Domain d1f2xk_: 1f2x K: [20511]
    VHh of antibody cab-ca05
  2. Domain d1f2xl_: 1f2x L: [20512]
    VHh of antibody cab-ca05
3. Domain for 1g6v:
  - Domain d1g6vk_: 1g6v K: [20513]
    Other proteins in same PDB: d1g6va_
    cVH of antibody cab-ca05
    complexed with zn
4. Domains for 1jto:
  1. Domain d1jtoa_: 1jto A: [67274]
    Other proteins in same PDB: d1jtol_, d1jtom_
    anti-lysozyme VHh domain
  2. Domain d1jtob_: 1jto B: [67275]
    Other proteins in same PDB: d1jtol_, d1jtom_
    anti-lysozyme VHh domain
5. Domains for 1jtp:
  1. Domain d1jtpa_: 1jtp A: [67278]
    Other proteins in same PDB: d1jtpl_, d1jtpm_
    anti-lysozyme VHh domain
    complexed with fmt, na
  2. Domain d1jtpb_: 1jtp B: [67279]
    Other proteins in same PDB: d1jtpl_, d1jtpm_
    anti-lysozyme VHh domain
    complexed with fmt, na
6. Domain for 1jtt:
  - Domain d1jtta_: 1jtt A: [67282]
    Other proteins in same PDB: d1jttl_
    anti-lysozyme VHh domain
    complexed with fmt, na
7. Domains for 1kxq:
  1. Domain d1kxqe_: 1kxq E: [73171]
    Other proteins in same PDB: d1kxqa1, d1kxqa2, d1kxqb1, d1kxqb2, d1kxqc1, d1kxqc2, d1kxqd1, d1kxqd2
    VHh CABAMD9 against alpha-amylase
    complexed with ca, cl
  2. Domain d1kxqf_: 1kxq F: [73172]
    Other proteins in same PDB: d1kxqa1, d1kxqa2, d1kxqb1, d1kxqb2, d1kxqc1, d1kxqc2, d1kxqd1, d1kxqd2
    VHh CABAMD9 against alpha-amylase
    complexed with ca, cl
  3. Domain d1kxqg_: 1kxq G: [73173]
    Other proteins in same PDB: d1kxqa1, d1kxqa2, d1kxqb1, d1kxqb2, d1kxqc1, d1kxqc2, d1kxqd1, d1kxqd2
    VHh CABAMD9 against alpha-amylase
    complexed with ca, cl
  4. Domain d1kxqh_: 1kxq H: [73174]
    Other proteins in same PDB: d1kxqa1, d1kxqa2, d1kxqb1, d1kxqb2, d1kxqc1, d1kxqc2, d1kxqd1, d1kxqd2
    VHh CABAMD9 against alpha-amylase
    complexed with ca, cl
8. Domains for 1kxt:
  1. Domain d1kxtb_: 1kxt B: [73179]
    Other proteins in same PDB: d1kxta1, d1kxta2, d1kxtc1, d1kxtc2, d1kxte1, d1kxte2
    VHh against alpha-amylase
    complexed with ca, cl
  2. Domain d1kxtd_: 1kxt D: [73182]
    Other proteins in same PDB: d1kxta1, d1kxta2, d1kxtc1, d1kxtc2, d1kxte1, d1kxte2
    VHh against alpha-amylase
    complexed with ca, cl
  3. Domain d1kxtf_: 1kxt F: [73185]
    Other proteins in same PDB: d1kxta1, d1kxta2, d1kxtc1, d1kxtc2, d1kxte1, d1kxte2
    VHh against alpha-amylase
    complexed with ca, cl
9. Domains for 1kxv:
  1. Domain d1kxvc_: 1kxv C: [73190]
    Other proteins in same PDB: d1kxva1, d1kxva2, d1kxvb1, d1kxvb2
    VHh CAB10 against alpha-amylase
  2. Domain d1kxvd_: 1kxv D: [73191]
    Other proteins in same PDB: d1kxva1, d1kxva2, d1kxvb1, d1kxvb2
    VHh CAB10 against alpha-amylase
10. Domains for 1mel:
  1. Domain d1mela_: 1mel A: [20505]
    Other proteins in same PDB: d1mell_, d1melm_
    anti-lysozyme VHh domain
  2. Domain d1melb_: 1mel B: [20506]
    Other proteins in same PDB: d1mell_, d1melm_
    anti-lysozyme VHh domain
11. Domains for 1mvf:
  1. Domain d1mvfa_: 1mvf A: [85141]
    Other proteins in same PDB: d1mvfd_, d1mvfe_
    VHh against MazE addiction antidote
  2. Domain d1mvfb_: 1mvf B: [85142]
    Other proteins in same PDB: d1mvfd_, d1mvfe_
    VHh against MazE addiction antidote
12. Domain for 1op9:
  - Domain d1op9a_: 1op9 A: [93398]
    Other proteins in same PDB: d1op9b_
    anti-lysozyme Hl6 VHh domain
13. Domain for 1ri8:
  - Domain d1ri8a1: 1ri8 A:2-125 [144369]
    Other proteins in same PDB: d1ri8b1
    complexed with gol
14. Domain for 1rjc:
  - Domain d1rjca1: 1rjc A:2-127 [144370]
    Other proteins in same PDB: d1rjcb1
    complexed with gol, po4
15. Domain for 1xfp:
  - Domain d1xfpa_: 1xfp A: [109587]
    Other proteins in same PDB: d1xfpl_
    complexed with fmt; mutant
16. Domain for 1zmy:
  - Domain d1zmya1: 1zmy A:1-133 [144746]
    Other proteins in same PDB: d1zmyl1, d1zmym1
17. Domain for 1zv5:
  - Domain d1zv5a1: 1zv5 A:2-120 [144771]
    Other proteins in same PDB: d1zv5l1
    complexed with po4
18. Domain for 1zvh:
  - Domain d1zvha1: 1zvh A:2-124 [144772]
    Other proteins in same PDB: d1zvhl1
19. Domain for 1zvy:
  - Domain d1zvya1: 1zvy A:2-125 [144780]
    Other proteins in same PDB: d1zvyb1
    complexed with gol, po4
Human (Homo sapiens) [TaxId:9606] [158863] (1 PDB entry)
- Domains for 3bn9:
  1. Domain d3bn9d1: 3bn9 D:1-113 [155426]
    Other proteins in same PDB: d3bn9a_, d3bn9b_, d3bn9d2, d3bn9f2
    automatically matched to d1qd0a_
    complexed with edo, so4
  2. Domain d3bn9f1: 3bn9 F:1-113 [155428]
    Other proteins in same PDB: d3bn9a_, d3bn9b_, d3bn9d2, d3bn9f2
    automatically matched to d1qd0a_
    complexed with edo, so4

Llama (Lama glama) [TaxId:9844] [88565] (8 PDB entries)

Domain for 1g9e:
- Domain d1g9ea_: 1g9e A: [76216]
  anti-gonadotropin alpha subunit VHh domain
Domain for 1hcv:
- Domain d1hcva_: 1hcv A: [20514]
  anti-gonadotropin alpha subunit VHh domain
Domain for 1i3u:
- Domain d1i3ua_: 1i3u A: [61636]
  dye RR1-binding VHh domain
  complexed with rr1, so4
Domains for 1i3v:
1. Domain d1i3va_: 1i3v A: [61637]
  dye RR1-binding VHh domain
2. Domain d1i3vb_: 1i3v B: [61638]
  dye RR1-binding VHh domain
Domain for 1ieh:
- Domain d1ieha_: 1ieh A: [71199]
  VHh BRUC.D4.4
Domain for 1qd0:
- Domain d1qd0a_: 1qd0 A: [20515]
  anti-RR6 VH domain
  complexed with cu, rr6
Domain for 1sjv:
- Domain d1sjva_: 1sjv A: [105662]
  swapped dimer

Domains for 1za3:

Domain d1za3b1: 1za3 B:1-113 [124789]
Other proteins in same PDB: d1za3a1, d1za3a2, d1za3b2, d1za3h2, d1za3l1, d1za3l2, d1za3r1, d1za3r2, d1za3r3, d1za3s1, d1za3s2, d1za3s3
automatically matched to d1i3va_

Domain d1za3h1: 1za3 H:1-113 [124791]
Other proteins in same PDB: d1za3a1, d1za3a2, d1za3b2, d1za3h2, d1za3l1, d1za3l2, d1za3r1, d1za3r2, d1za3r3, d1za3s1, d1za3s2, d1za3s3
automatically matched to d1i3va_

More info for Protein Camelid IG heavy chain variable domain, VHh from b.1.1.1: V set domains (antibody variable domain-like)

Timeline for Protein Camelid IG heavy chain variable domain, VHh from b.1.1.1: V set domains (antibody variable domain-like):

Protein Camelid IG heavy chain variable domain, VHh from b.1.1.1: V set domains (antibody variable domain-like) first appeared in SCOP 1.65
Protein Camelid IG heavy chain variable domain, VHh from b.1.1.1: V set domains (antibody variable domain-like) appears in SCOP 1.75
Protein Camelid IG heavy chain variable domain, VHh from b.1.1.1: V set domains (antibody variable domain-like) appears in SCOPe 2.02
Protein Camelid IG heavy chain variable domain, VHh from b.1.1.1: V set domains (antibody variable domain-like) appears in the current release, SCOPe 2.08