Lineage for Species: Mouse (Mus musculus), cluster 3.1 [TaxId: 10090]

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2344608Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2344609Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2344610Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2344816Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2345282Species Mouse (Mus musculus), cluster 3.1 [TaxId:10090] [88551] (31 PDB entries)
    SQ NA # natural chimera; best hits are: Uniprot P01751 (Ig heavy chain V region B1-8/186-2) and Uniprot P01864 (Ig gamma-2A chain C region secreted form)

PDB entries in Species: Mouse (Mus musculus), cluster 3.1 [TaxId: 10090]:

  1. Domain(s) for 12e8:
    1. 2345286Domain d12e8h1: 12e8 H:1-114 [20269]
      Other proteins in same PDB: d12e8h2, d12e8l1, d12e8l2, d12e8m1, d12e8m2, d12e8p2
      part of Fab 2E8 specific to the low density lipoprotein receptor binding region of apolipoprotein E
    2. 2345287Domain d12e8p1: 12e8 P:1-114 [20271]
      Other proteins in same PDB: d12e8h2, d12e8l1, d12e8l2, d12e8m1, d12e8m2, d12e8p2
      part of Fab 2E8 specific to the low density lipoprotein receptor binding region of apolipoprotein E
  2. Domain(s) for 15c8:
  3. Domain(s) for 1a3r:
  4. Domain(s) for 1a5f:
  5. Domain(s) for 1ahw:
    1. 2345318Domain d1ahwb1: 1ahw B:1-117 [20219]
      Other proteins in same PDB: d1ahwa1, d1ahwa2, d1ahwb2, d1ahwc1, d1ahwc2, d1ahwd1, d1ahwd2, d1ahwe2, d1ahwf1, d1ahwf2
      part of anti-human tissue factor Fab 5G9
    2. 2345319Domain d1ahwe1: 1ahw E:1-117 [20221]
      Other proteins in same PDB: d1ahwa1, d1ahwa2, d1ahwb2, d1ahwc1, d1ahwc2, d1ahwd1, d1ahwd2, d1ahwe2, d1ahwf1, d1ahwf2
      part of anti-human tissue factor Fab 5G9
  6. Domain(s) for 1aj7:
  7. Domain(s) for 1ap2:
    1. 2345307Domain d1ap2b_: 1ap2 B: [20183]
      Other proteins in same PDB: d1ap2a_, d1ap2c_
      part of P-glycoprotein-specific scFv C219
    2. 2345308Domain d1ap2d_: 1ap2 D: [20185]
      Other proteins in same PDB: d1ap2a_, d1ap2c_
      part of P-glycoprotein-specific scFv C219
  8. Domain(s) for 1bbd:
  9. Domain(s) for 1cr9:
  10. Domain(s) for 1cu4:
  11. Domain(s) for 1dvf:
  12. Domain(s) for 1dzb:
    1. 2345292Domain d1dzba1: 1dzb A:1-117 [20488]
      Other proteins in same PDB: d1dzba2, d1dzbb2, d1dzbx_, d1dzby_
      part of anti-lysozyme scFv 1F9
    2. 2345293Domain d1dzbb1: 1dzb B:1-117 [20490]
      Other proteins in same PDB: d1dzba2, d1dzbb2, d1dzbx_, d1dzby_
      part of anti-lysozyme scFv 1F9
  13. Domain(s) for 1fgn:
  14. Domain(s) for 1gaf:
  15. Domain(s) for 1hkl:
  16. Domain(s) for 1il1:
  17. Domain(s) for 1jnl:
  18. Domain(s) for 1jnn:
  19. Domain(s) for 1k6q:
  20. Domain(s) for 1moe:
    1. 2345320Domain d1moea2: 1moe A:120-240 [85031]
      Other proteins in same PDB: d1moea1, d1moeb1
      part of anti-CEA scFv T84.66; VL to VH linkage: linker residues 112-119; assembles as a diabody
      complexed with so4
    2. 2345321Domain d1moeb2: 1moe B:120-240 [85033]
      Other proteins in same PDB: d1moea1, d1moeb1
      part of anti-CEA scFv T84.66; VL to VH linkage: linker residues 112-119; assembles as a diabody
      complexed with so4
  21. Domain(s) for 1qbl:
  22. Domain(s) for 1qbm:
  23. Domain(s) for 1qok:
  24. Domain(s) for 1wej:
  25. Domain(s) for 25c8:
  26. Domain(s) for 2ap2:
    1. 2345305Domain d2ap2b_: 2ap2 B: [20179]
      Other proteins in same PDB: d2ap2a_, d2ap2c_
      part of P-glycoprotein-specific scFv C219
    2. 2345306Domain d2ap2d_: 2ap2 D: [20181]
      Other proteins in same PDB: d2ap2a_, d2ap2c_
      part of P-glycoprotein-specific scFv C219
  27. Domain(s) for 2bdn:
  28. Domain(s) for 2gsi:
    1. 2345309Domain d2gsib1: 2gsi B:2-114 [145221]
      Other proteins in same PDB: d2gsia1, d2gsia2, d2gsib2, d2gsic1, d2gsic2, d2gsid2, d2gsie1, d2gsie2, d2gsif2, d2gsig1, d2gsig2, d2gsih2
      complexed with na
    2. 2345310Domain d2gsid1: 2gsi D:2-114 [145223]
      Other proteins in same PDB: d2gsia1, d2gsia2, d2gsib2, d2gsic1, d2gsic2, d2gsid2, d2gsie1, d2gsie2, d2gsif2, d2gsig1, d2gsig2, d2gsih2
      automatically matched to 2GSI B:2-114
      complexed with na
    3. 2345311Domain d2gsif1: 2gsi F:2-114 [145225]
      Other proteins in same PDB: d2gsia1, d2gsia2, d2gsib2, d2gsic1, d2gsic2, d2gsid2, d2gsie1, d2gsie2, d2gsif2, d2gsig1, d2gsig2, d2gsih2
      automatically matched to 2GSI B:2-114
      complexed with na
    4. 2345312Domain d2gsih1: 2gsi H:2-114 [145227]
      Other proteins in same PDB: d2gsia1, d2gsia2, d2gsib2, d2gsic1, d2gsic2, d2gsid2, d2gsie1, d2gsie2, d2gsif2, d2gsig1, d2gsig2, d2gsih2
      automatically matched to 2GSI B:2-114
      complexed with na
  29. Domain(s) for 2hh0:
  30. Domain(s) for 2rcs:
  31. Domain(s) for 35c8:

More info for Species Mouse (Mus musculus), cluster 3.1 [TaxId:10090] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH

Timeline for Species Mouse (Mus musculus), cluster 3.1 [TaxId:10090] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH: