Lineage for Species: Human (Homo sapiens), cluster 3 [TaxId: 9606]

  1. Root: SCOPe 2.01
  2. 929298Class b: All beta proteins [48724] (174 folds)
  3. 929299Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 929300Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 929301Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 929498Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 929678Species Human (Homo sapiens), cluster 3 [TaxId:9606] [88547] (33 PDB entries)
    Uniprot Q6N089 20-243 # 95% sequence identity; natural chimera: antibody heavy chain (Fab HYB3)

PDB entries in Species: Human (Homo sapiens), cluster 3 [TaxId: 9606]:

  1. Domain(s) for 1adq:
  2. Domain(s) for 1aqk:
  3. Domain(s) for 1dee:
    1. 929721Domain d1deeb1: 1dee B:501-621 [20443]
      Other proteins in same PDB: d1deea1, d1deea2, d1deeb2, d1deec1, d1deec2, d1deed2, d1deee1, d1deee2, d1deef2, d1deeg_, d1deeh_
      part of IgM RF 2A2
    2. 929722Domain d1deed1: 1dee D:1501-1621 [20445]
      Other proteins in same PDB: d1deea1, d1deea2, d1deeb2, d1deec1, d1deec2, d1deed2, d1deee1, d1deee2, d1deef2, d1deeg_, d1deeh_
      part of IgM RF 2A2
    3. 929723Domain d1deef1: 1dee F:2501-2621 [20447]
      Other proteins in same PDB: d1deea1, d1deea2, d1deeb2, d1deec1, d1deec2, d1deed2, d1deee1, d1deee2, d1deef2, d1deeg_, d1deeh_
      part of IgM RF 2A2
  4. Domain(s) for 1dfb:
  5. Domain(s) for 1dql:
  6. Domain(s) for 1hez:
    1. 929726Domain d1hezb1: 1hez B:1-121 [60985]
      Other proteins in same PDB: d1heza1, d1heza2, d1hezb2, d1hezc1, d1hezc2, d1hezd2, d1heze_
      part of IgM RF 2A2
      complexed with imd
    2. 929727Domain d1hezd1: 1hez D:1-121 [60989]
      Other proteins in same PDB: d1heza1, d1heza2, d1hezb2, d1hezc1, d1hezc2, d1hezd2, d1heze_
      part of IgM RF 2A2
      complexed with imd
  7. Domain(s) for 1igm:
  8. Domain(s) for 1nl0:
  9. Domain(s) for 1u6a:
  10. Domain(s) for 1w72:
    1. 929684Domain d1w72h1: 1w72 H:1-113 [114299]
      Other proteins in same PDB: d1w72a1, d1w72a2, d1w72b_, d1w72d1, d1w72d2, d1w72e_, d1w72h2, d1w72i2, d1w72l1, d1w72l2, d1w72m1, d1w72m2
      complexed with gol
    2. 929685Domain d1w72i1: 1w72 I:1-113 [114301]
      Other proteins in same PDB: d1w72a1, d1w72a2, d1w72b_, d1w72d1, d1w72d2, d1w72e_, d1w72h2, d1w72i2, d1w72l1, d1w72l2, d1w72m1, d1w72m2
      complexed with gol
  11. Domain(s) for 1y0l:
    1. 929691Domain d1y0lb1: 1y0l B:1-113 [122488]
      Other proteins in same PDB: d1y0la1, d1y0la2, d1y0lb2, d1y0lc1, d1y0lc2, d1y0ld2, d1y0le1, d1y0le2, d1y0lf2, d1y0lh2, d1y0ll1, d1y0ll2
      automatically matched to d1aqkh1
      complexed with cl, han
    2. 929692Domain d1y0ld1: 1y0l D:1-113 [122492]
      Other proteins in same PDB: d1y0la1, d1y0la2, d1y0lb2, d1y0lc1, d1y0lc2, d1y0ld2, d1y0le1, d1y0le2, d1y0lf2, d1y0lh2, d1y0ll1, d1y0ll2
      automatically matched to d1aqkh1
      complexed with cl, han
    3. 929693Domain d1y0lf1: 1y0l F:1-113 [122496]
      Other proteins in same PDB: d1y0la1, d1y0la2, d1y0lb2, d1y0lc1, d1y0lc2, d1y0ld2, d1y0le1, d1y0le2, d1y0lf2, d1y0lh2, d1y0ll1, d1y0ll2
      automatically matched to d1aqkh1
      complexed with cl, han
    4. 929694Domain d1y0lh1: 1y0l H:1-113 [122498]
      Other proteins in same PDB: d1y0la1, d1y0la2, d1y0lb2, d1y0lc1, d1y0lc2, d1y0ld2, d1y0le1, d1y0le2, d1y0lf2, d1y0lh2, d1y0ll1, d1y0ll2
      automatically matched to d1aqkh1
      complexed with cl, han
  12. Domain(s) for 1y18:
    1. 929730Domain d1y18b1: 1y18 B:1-113 [122523]
      Other proteins in same PDB: d1y18a1, d1y18a2, d1y18b2, d1y18c1, d1y18c2, d1y18d2, d1y18e1, d1y18e2, d1y18f2, d1y18h2, d1y18l1, d1y18l2
      automatically matched to d1aqkh1
      complexed with cl, han; mutant
    2. 929731Domain d1y18d1: 1y18 D:1-113 [122527]
      Other proteins in same PDB: d1y18a1, d1y18a2, d1y18b2, d1y18c1, d1y18c2, d1y18d2, d1y18e1, d1y18e2, d1y18f2, d1y18h2, d1y18l1, d1y18l2
      automatically matched to d1aqkh1
      complexed with cl, han; mutant
    3. 929732Domain d1y18f1: 1y18 F:1-113 [122531]
      Other proteins in same PDB: d1y18a1, d1y18a2, d1y18b2, d1y18c1, d1y18c2, d1y18d2, d1y18e1, d1y18e2, d1y18f2, d1y18h2, d1y18l1, d1y18l2
      automatically matched to d1aqkh1
      complexed with cl, han; mutant
    4. 929733Domain d1y18h1: 1y18 H:1-113 [122533]
      Other proteins in same PDB: d1y18a1, d1y18a2, d1y18b2, d1y18c1, d1y18c2, d1y18d2, d1y18e1, d1y18e2, d1y18f2, d1y18h2, d1y18l1, d1y18l2
      automatically matched to d1aqkh1
      complexed with cl, han; mutant
  13. Domain(s) for 1zls:
  14. Domain(s) for 1zlu:
    1. 929743Domain d1zluh1: 1zlu H:1-112 [125258]
      Other proteins in same PDB: d1zluh2, d1zlum2
      automatically matched to d1aqkh1
    2. 929744Domain d1zlum1: 1zlu M:1-112 [125260]
      Other proteins in same PDB: d1zluh2, d1zlum2
      automatically matched to d1aqkh1
  15. Domain(s) for 1zlv:
    1. 929688Domain d1zlvh1: 1zlv H:1-112 [125262]
      Other proteins in same PDB: d1zlvh2, d1zlvm2
      automatically matched to d1aqkh1
      complexed with man
    2. 929689Domain d1zlvm1: 1zlv M:1-112 [125264]
      Other proteins in same PDB: d1zlvh2, d1zlvm2
      automatically matched to d1aqkh1
      complexed with man
  16. Domain(s) for 1zlw:
    1. 929739Domain d1zlwh1: 1zlw H:1-112 [125266]
      Other proteins in same PDB: d1zlwh2, d1zlwm2
      automatically matched to d1aqkh1
      complexed with man
    2. 929740Domain d1zlwm1: 1zlw M:1-112 [125268]
      Other proteins in same PDB: d1zlwh2, d1zlwm2
      automatically matched to d1aqkh1
      complexed with man
  17. Domain(s) for 2fb4:
  18. Domain(s) for 2ghw:
    1. 929709Domain d2ghwb2: 2ghw B:1-117 [145199]
      Other proteins in same PDB: d2ghwa_, d2ghwb1, d2ghwc_, d2ghwd1
      complexed with cl
    2. 929710Domain d2ghwd2: 2ghw D:1-117 [145201]
      Other proteins in same PDB: d2ghwa_, d2ghwb1, d2ghwc_, d2ghwd1
      automatically matched to 2GHW B:1-117
      complexed with cl
  19. Domain(s) for 2ig2:
  20. Domain(s) for 2jb5:
  21. Domain(s) for 2jb6:
    1. 929741Domain d2jb6b1: 2jb6 B:3-120 [147957]
      Other proteins in same PDB: d2jb6b2, d2jb6h2
      automatically matched to d1nl0h1
      complexed with t5c
    2. 929742Domain d2jb6h1: 2jb6 H:3-120 [147959]
      Other proteins in same PDB: d2jb6b2, d2jb6h2
      automatically matched to d1nl0h1
      complexed with t5c
  22. Domain(s) for 2oqj:
    1. 929735Domain d2oqjb1: 2oqj B:1-112 [148984]
      Other proteins in same PDB: d2oqjb2, d2oqje2, d2oqjh2, d2oqjk2
      automatically matched to d1aqkh1
    2. 929736Domain d2oqje1: 2oqj E:1-112 [148986]
      Other proteins in same PDB: d2oqjb2, d2oqje2, d2oqjh2, d2oqjk2
      automatically matched to d1aqkh1
    3. 929737Domain d2oqjh1: 2oqj H:1-112 [148988]
      Other proteins in same PDB: d2oqjb2, d2oqje2, d2oqjh2, d2oqjk2
      automatically matched to d1aqkh1
    4. 929738Domain d2oqjk1: 2oqj K:1-112 [148990]
      Other proteins in same PDB: d2oqjb2, d2oqje2, d2oqjh2, d2oqjk2
      automatically matched to d1aqkh1
  23. Domain(s) for 2qqn:
  24. Domain(s) for 3b2u:
    1. 929713Domain d3b2uc1: 3b2u C:1-121 [154774]
      Other proteins in same PDB: d3b2ua1, d3b2ua2, d3b2ub1, d3b2ub2, d3b2uc2, d3b2ue1, d3b2ue2, d3b2uf2, d3b2uh2, d3b2ui1, d3b2ui2, d3b2uj2, d3b2um1, d3b2um2, d3b2un2, d3b2up1, d3b2up2, d3b2uq2, d3b2us1, d3b2us2, d3b2ut2, d3b2uv1, d3b2uv2, d3b2uw2
      automatically matched to d1deeb1
      complexed with nag, so4
    2. 929714Domain d3b2uf1: 3b2u F:1-121 [154778]
      Other proteins in same PDB: d3b2ua1, d3b2ua2, d3b2ub1, d3b2ub2, d3b2uc2, d3b2ue1, d3b2ue2, d3b2uf2, d3b2uh2, d3b2ui1, d3b2ui2, d3b2uj2, d3b2um1, d3b2um2, d3b2un2, d3b2up1, d3b2up2, d3b2uq2, d3b2us1, d3b2us2, d3b2ut2, d3b2uv1, d3b2uv2, d3b2uw2
      automatically matched to d1deeb1
      complexed with nag, so4
    3. 929715Domain d3b2uh1: 3b2u H:1-121 [154780]
      Other proteins in same PDB: d3b2ua1, d3b2ua2, d3b2ub1, d3b2ub2, d3b2uc2, d3b2ue1, d3b2ue2, d3b2uf2, d3b2uh2, d3b2ui1, d3b2ui2, d3b2uj2, d3b2um1, d3b2um2, d3b2un2, d3b2up1, d3b2up2, d3b2uq2, d3b2us1, d3b2us2, d3b2ut2, d3b2uv1, d3b2uv2, d3b2uw2
      automatically matched to d1deeb1
      complexed with nag, so4
    4. 929716Domain d3b2uj1: 3b2u J:1-121 [154784]
      Other proteins in same PDB: d3b2ua1, d3b2ua2, d3b2ub1, d3b2ub2, d3b2uc2, d3b2ue1, d3b2ue2, d3b2uf2, d3b2uh2, d3b2ui1, d3b2ui2, d3b2uj2, d3b2um1, d3b2um2, d3b2un2, d3b2up1, d3b2up2, d3b2uq2, d3b2us1, d3b2us2, d3b2ut2, d3b2uv1, d3b2uv2, d3b2uw2
      automatically matched to d1deeb1
      complexed with nag, so4
    5. 929717Domain d3b2un1: 3b2u N:1-121 [154788]
      Other proteins in same PDB: d3b2ua1, d3b2ua2, d3b2ub1, d3b2ub2, d3b2uc2, d3b2ue1, d3b2ue2, d3b2uf2, d3b2uh2, d3b2ui1, d3b2ui2, d3b2uj2, d3b2um1, d3b2um2, d3b2un2, d3b2up1, d3b2up2, d3b2uq2, d3b2us1, d3b2us2, d3b2ut2, d3b2uv1, d3b2uv2, d3b2uw2
      automatically matched to d1deeb1
      complexed with nag, so4
    6. 929718Domain d3b2uq1: 3b2u Q:1-121 [154792]
      Other proteins in same PDB: d3b2ua1, d3b2ua2, d3b2ub1, d3b2ub2, d3b2uc2, d3b2ue1, d3b2ue2, d3b2uf2, d3b2uh2, d3b2ui1, d3b2ui2, d3b2uj2, d3b2um1, d3b2um2, d3b2un2, d3b2up1, d3b2up2, d3b2uq2, d3b2us1, d3b2us2, d3b2ut2, d3b2uv1, d3b2uv2, d3b2uw2
      automatically matched to d1deeb1
      complexed with nag, so4
    7. 929719Domain d3b2ut1: 3b2u T:1-121 [154796]
      Other proteins in same PDB: d3b2ua1, d3b2ua2, d3b2ub1, d3b2ub2, d3b2uc2, d3b2ue1, d3b2ue2, d3b2uf2, d3b2uh2, d3b2ui1, d3b2ui2, d3b2uj2, d3b2um1, d3b2um2, d3b2un2, d3b2up1, d3b2up2, d3b2uq2, d3b2us1, d3b2us2, d3b2ut2, d3b2uv1, d3b2uv2, d3b2uw2
      automatically matched to d1deeb1
      complexed with nag, so4
    8. 929720Domain d3b2uw1: 3b2u W:1-121 [154800]
      Other proteins in same PDB: d3b2ua1, d3b2ua2, d3b2ub1, d3b2ub2, d3b2uc2, d3b2ue1, d3b2ue2, d3b2uf2, d3b2uh2, d3b2ui1, d3b2ui2, d3b2uj2, d3b2um1, d3b2um2, d3b2un2, d3b2up1, d3b2up2, d3b2uq2, d3b2us1, d3b2us2, d3b2ut2, d3b2uv1, d3b2uv2, d3b2uw2
      automatically matched to d1deeb1
      complexed with nag, so4
  25. Domain(s) for 3b2v:
  26. Domain(s) for 3bky:
  27. Domain(s) for 3c08:
  28. Domain(s) for 3c09:
    1. 929747Domain d3c09c1: 3c09 C:2-121 [155813]
      Other proteins in same PDB: d3c09a1, d3c09a2, d3c09c2, d3c09d1, d3c09d2, d3c09h2
      automatically matched to d8fabb1
      complexed with bma, man, nag
    2. 929748Domain d3c09h1: 3c09 H:2-121 [155817]
      Other proteins in same PDB: d3c09a1, d3c09a2, d3c09c2, d3c09d1, d3c09d2, d3c09h2
      automatically matched to d8fabb1
      complexed with bma, man, nag
  29. Domain(s) for 3cfj:
    1. 929697Domain d3cfjb1: 3cfj B:1-113 [156567]
      Other proteins in same PDB: d3cfja1, d3cfja2, d3cfjb2, d3cfjc1, d3cfjc2, d3cfjd2, d3cfje1, d3cfje2, d3cfjf2, d3cfjh2, d3cfjl1, d3cfjl2
      automatically matched to d1aqkh1
      complexed with gol, so4
    2. 929698Domain d3cfjd1: 3cfj D:1-113 [156571]
      Other proteins in same PDB: d3cfja1, d3cfja2, d3cfjb2, d3cfjc1, d3cfjc2, d3cfjd2, d3cfje1, d3cfje2, d3cfjf2, d3cfjh2, d3cfjl1, d3cfjl2
      automatically matched to d1aqkh1
      complexed with gol, so4
    3. 929699Domain d3cfjf1: 3cfj F:1-113 [156575]
      Other proteins in same PDB: d3cfja1, d3cfja2, d3cfjb2, d3cfjc1, d3cfjc2, d3cfjd2, d3cfje1, d3cfje2, d3cfjf2, d3cfjh2, d3cfjl1, d3cfjl2
      automatically matched to d1aqkh1
      complexed with gol, so4
    4. 929700Domain d3cfjh1: 3cfj H:1-113 [156577]
      Other proteins in same PDB: d3cfja1, d3cfja2, d3cfjb2, d3cfjc1, d3cfjc2, d3cfjd2, d3cfje1, d3cfje2, d3cfjf2, d3cfjh2, d3cfjl1, d3cfjl2
      automatically matched to d1aqkh1
      complexed with gol, so4
  30. Domain(s) for 3cfk:
    1. 929701Domain d3cfkb1: 3cfk B:1-113 [156583]
      Other proteins in same PDB: d3cfka1, d3cfka2, d3cfkb2, d3cfkc1, d3cfkc2, d3cfkd2, d3cfke1, d3cfke2, d3cfkf2, d3cfkg1, d3cfkg2, d3cfkh2, d3cfki2, d3cfkj1, d3cfkj2, d3cfkk2, d3cfkl1, d3cfkl2, d3cfkm1, d3cfkm2, d3cfkn2, d3cfko1, d3cfko2, d3cfkp2
      automatically matched to d1aqkh1
      complexed with b3p, cd, gol
    2. 929702Domain d3cfkd1: 3cfk D:1-113 [156587]
      Other proteins in same PDB: d3cfka1, d3cfka2, d3cfkb2, d3cfkc1, d3cfkc2, d3cfkd2, d3cfke1, d3cfke2, d3cfkf2, d3cfkg1, d3cfkg2, d3cfkh2, d3cfki2, d3cfkj1, d3cfkj2, d3cfkk2, d3cfkl1, d3cfkl2, d3cfkm1, d3cfkm2, d3cfkn2, d3cfko1, d3cfko2, d3cfkp2
      automatically matched to d1aqkh1
      complexed with b3p, cd, gol
    3. 929703Domain d3cfkf1: 3cfk F:1-113 [156591]
      Other proteins in same PDB: d3cfka1, d3cfka2, d3cfkb2, d3cfkc1, d3cfkc2, d3cfkd2, d3cfke1, d3cfke2, d3cfkf2, d3cfkg1, d3cfkg2, d3cfkh2, d3cfki2, d3cfkj1, d3cfkj2, d3cfkk2, d3cfkl1, d3cfkl2, d3cfkm1, d3cfkm2, d3cfkn2, d3cfko1, d3cfko2, d3cfkp2
      automatically matched to d1aqkh1
      complexed with b3p, cd, gol
    4. 929704Domain d3cfkh1: 3cfk H:1-113 [156595]
      Other proteins in same PDB: d3cfka1, d3cfka2, d3cfkb2, d3cfkc1, d3cfkc2, d3cfkd2, d3cfke1, d3cfke2, d3cfkf2, d3cfkg1, d3cfkg2, d3cfkh2, d3cfki2, d3cfkj1, d3cfkj2, d3cfkk2, d3cfkl1, d3cfkl2, d3cfkm1, d3cfkm2, d3cfkn2, d3cfko1, d3cfko2, d3cfkp2
      automatically matched to d1aqkh1
      complexed with b3p, cd, gol
    5. 929705Domain d3cfki1: 3cfk I:1-113 [156597]
      Other proteins in same PDB: d3cfka1, d3cfka2, d3cfkb2, d3cfkc1, d3cfkc2, d3cfkd2, d3cfke1, d3cfke2, d3cfkf2, d3cfkg1, d3cfkg2, d3cfkh2, d3cfki2, d3cfkj1, d3cfkj2, d3cfkk2, d3cfkl1, d3cfkl2, d3cfkm1, d3cfkm2, d3cfkn2, d3cfko1, d3cfko2, d3cfkp2
      automatically matched to d1aqkh1
      complexed with b3p, cd, gol
    6. 929706Domain d3cfkk1: 3cfk K:1-113 [156601]
      Other proteins in same PDB: d3cfka1, d3cfka2, d3cfkb2, d3cfkc1, d3cfkc2, d3cfkd2, d3cfke1, d3cfke2, d3cfkf2, d3cfkg1, d3cfkg2, d3cfkh2, d3cfki2, d3cfkj1, d3cfkj2, d3cfkk2, d3cfkl1, d3cfkl2, d3cfkm1, d3cfkm2, d3cfkn2, d3cfko1, d3cfko2, d3cfkp2
      automatically matched to d1aqkh1
      complexed with b3p, cd, gol
    7. 929707Domain d3cfkn1: 3cfk N:1-113 [156607]
      Other proteins in same PDB: d3cfka1, d3cfka2, d3cfkb2, d3cfkc1, d3cfkc2, d3cfkd2, d3cfke1, d3cfke2, d3cfkf2, d3cfkg1, d3cfkg2, d3cfkh2, d3cfki2, d3cfkj1, d3cfkj2, d3cfkk2, d3cfkl1, d3cfkl2, d3cfkm1, d3cfkm2, d3cfkn2, d3cfko1, d3cfko2, d3cfkp2
      automatically matched to d1aqkh1
      complexed with b3p, cd, gol
    8. 929708Domain d3cfkp1: 3cfk P:1-113 [156611]
      Other proteins in same PDB: d3cfka1, d3cfka2, d3cfkb2, d3cfkc1, d3cfkc2, d3cfkd2, d3cfke1, d3cfke2, d3cfkf2, d3cfkg1, d3cfkg2, d3cfkh2, d3cfki2, d3cfkj1, d3cfkj2, d3cfkk2, d3cfkl1, d3cfkl2, d3cfkm1, d3cfkm2, d3cfkn2, d3cfko1, d3cfko2, d3cfkp2
      automatically matched to d1aqkh1
      complexed with b3p, cd, gol
  31. Domain(s) for 3dvg:
  32. Domain(s) for 3dvn:
    1. 929724Domain d3dvnb1: 3dvn B:2-120 [157896]
      Other proteins in same PDB: d3dvna1, d3dvna2, d3dvnb2, d3dvnh2, d3dvnl1, d3dvnl2, d3dvnu_, d3dvnv_, d3dvnx_, d3dvny_
      automatically matched to d1nl0h1
    2. 929725Domain d3dvnh1: 3dvn H:2-120 [157898]
      Other proteins in same PDB: d3dvna1, d3dvna2, d3dvnb2, d3dvnh2, d3dvnl1, d3dvnl2, d3dvnu_, d3dvnv_, d3dvnx_, d3dvny_
      automatically matched to d1nl0h1
  33. Domain(s) for 8fab:
    1. 929679Domain d8fabb1: 8fab B:1-121 [19773]
      Other proteins in same PDB: d8faba1, d8faba2, d8fabb2, d8fabc1, d8fabc2, d8fabd2
      part of Fab HIL
    2. 929680Domain d8fabd1: 8fab D:1-121 [19775]
      Other proteins in same PDB: d8faba1, d8faba2, d8fabb2, d8fabc1, d8fabc2, d8fabd2
      part of Fab HIL

More info for Species Human (Homo sapiens), cluster 3 [TaxId:9606] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH

Timeline for Species Human (Homo sapiens), cluster 3 [TaxId:9606] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH: