Lineage for Species: Human (Homo sapiens), cluster 3 [TaxId: 9606]

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 781542Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 781543Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 781544Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (32 proteins)
  6. 781740Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 781920Species Human (Homo sapiens), cluster 3 [TaxId:9606] [88547] (33 PDB entries)
    Uniprot Q6N089 20-243 # 95% sequence identity; natural chimera: antibody heavy chain (Fab HYB3)

PDB entries in Species: Human (Homo sapiens), cluster 3 [TaxId: 9606]:

  1. Domain(s) for 1adq:
  2. Domain(s) for 1aqk:
  3. Domain(s) for 1dee:
    1. 781952Domain d1deeb1: 1dee B:501-621 [20443]
      Other proteins in same PDB: d1deea1, d1deea2, d1deeb2, d1deec1, d1deec2, d1deed2, d1deee1, d1deee2, d1deef2, d1deeg_, d1deeh_
      part of IgM RF 2A2
    2. 781953Domain d1deed1: 1dee D:1501-1621 [20445]
      Other proteins in same PDB: d1deea1, d1deea2, d1deeb2, d1deec1, d1deec2, d1deed2, d1deee1, d1deee2, d1deef2, d1deeg_, d1deeh_
      part of IgM RF 2A2
    3. 781954Domain d1deef1: 1dee F:2501-2621 [20447]
      Other proteins in same PDB: d1deea1, d1deea2, d1deeb2, d1deec1, d1deec2, d1deed2, d1deee1, d1deee2, d1deef2, d1deeg_, d1deeh_
      part of IgM RF 2A2
  4. Domain(s) for 1dfb:
  5. Domain(s) for 1dql:
  6. Domain(s) for 1hez:
    1. 781967Domain d1hezb1: 1hez B:1-121 [60985]
      Other proteins in same PDB: d1heza1, d1heza2, d1hezb2, d1hezc1, d1hezc2, d1hezd2, d1heze_
      part of IgM RF 2A2
    2. 781968Domain d1hezd1: 1hez D:1-121 [60989]
      Other proteins in same PDB: d1heza1, d1heza2, d1hezb2, d1hezc1, d1hezc2, d1hezd2, d1heze_
      part of IgM RF 2A2
      complexed with imd
  7. Domain(s) for 1igm:
  8. Domain(s) for 1nl0:
  9. Domain(s) for 1u6a:
  10. Domain(s) for 1w72:
    1. 781923Domain d1w72h1: 1w72 H:1-113 [114299]
      Other proteins in same PDB: d1w72a1, d1w72a2, d1w72b_, d1w72d1, d1w72d2, d1w72e_, d1w72h2, d1w72i2, d1w72l1, d1w72l2, d1w72m1, d1w72m2
    2. 781924Domain d1w72i1: 1w72 I:1-113 [114301]
      Other proteins in same PDB: d1w72a1, d1w72a2, d1w72b_, d1w72d1, d1w72d2, d1w72e_, d1w72h2, d1w72i2, d1w72l1, d1w72l2, d1w72m1, d1w72m2
      complexed with gol
  11. Domain(s) for 1y0l:
    1. 781930Domain d1y0lb1: 1y0l B:1-113 [122488]
      Other proteins in same PDB: d1y0la1, d1y0la2, d1y0lb2, d1y0lc1, d1y0lc2, d1y0ld2, d1y0le1, d1y0le2, d1y0lf2, d1y0lh2, d1y0ll1, d1y0ll2
      automatically matched to d1aqkh1
      complexed with cl, han
    2. 781931Domain d1y0ld1: 1y0l D:1-113 [122492]
      Other proteins in same PDB: d1y0la1, d1y0la2, d1y0lb2, d1y0lc1, d1y0lc2, d1y0ld2, d1y0le1, d1y0le2, d1y0lf2, d1y0lh2, d1y0ll1, d1y0ll2
      automatically matched to d1aqkh1
      complexed with cl, han
    3. 781932Domain d1y0lf1: 1y0l F:1-113 [122496]
      Other proteins in same PDB: d1y0la1, d1y0la2, d1y0lb2, d1y0lc1, d1y0lc2, d1y0ld2, d1y0le1, d1y0le2, d1y0lf2, d1y0lh2, d1y0ll1, d1y0ll2
      automatically matched to d1aqkh1
      complexed with cl, han
    4. 781933Domain d1y0lh1: 1y0l H:1-113 [122498]
      Other proteins in same PDB: d1y0la1, d1y0la2, d1y0lb2, d1y0lc1, d1y0lc2, d1y0ld2, d1y0le1, d1y0le2, d1y0lf2, d1y0lh2, d1y0ll1, d1y0ll2
      automatically matched to d1aqkh1
      complexed with cl, han
  12. Domain(s) for 1y18:
    1. 781971Domain d1y18b1: 1y18 B:1-113 [122523]
      Other proteins in same PDB: d1y18a1, d1y18a2, d1y18b2, d1y18c1, d1y18c2, d1y18d2, d1y18e1, d1y18e2, d1y18f2, d1y18h2, d1y18l1, d1y18l2
      automatically matched to d1aqkh1
      complexed with cl, han; mutant
    2. 781972Domain d1y18d1: 1y18 D:1-113 [122527]
      Other proteins in same PDB: d1y18a1, d1y18a2, d1y18b2, d1y18c1, d1y18c2, d1y18d2, d1y18e1, d1y18e2, d1y18f2, d1y18h2, d1y18l1, d1y18l2
      automatically matched to d1aqkh1
      complexed with cl, han; mutant
    3. 781973Domain d1y18f1: 1y18 F:1-113 [122531]
      Other proteins in same PDB: d1y18a1, d1y18a2, d1y18b2, d1y18c1, d1y18c2, d1y18d2, d1y18e1, d1y18e2, d1y18f2, d1y18h2, d1y18l1, d1y18l2
      automatically matched to d1aqkh1
      complexed with cl, han; mutant
    4. 781974Domain d1y18h1: 1y18 H:1-113 [122533]
      Other proteins in same PDB: d1y18a1, d1y18a2, d1y18b2, d1y18c1, d1y18c2, d1y18d2, d1y18e1, d1y18e2, d1y18f2, d1y18h2, d1y18l1, d1y18l2
      automatically matched to d1aqkh1
      complexed with cl, han; mutant
  13. Domain(s) for 1zls:
  14. Domain(s) for 1zlu:
    1. 781987Domain d1zluh1: 1zlu H:1-112 [125258]
      Other proteins in same PDB: d1zluh2, d1zlum2
      automatically matched to d1aqkh1
      complexed with man
    2. 781988Domain d1zlum1: 1zlu M:1-112 [125260]
      Other proteins in same PDB: d1zluh2, d1zlum2
      automatically matched to d1aqkh1
      complexed with man
  15. Domain(s) for 1zlv:
    1. 781935Domain d1zlvh1: 1zlv H:1-112 [125262]
      Other proteins in same PDB: d1zlvh2, d1zlvm2
      automatically matched to d1aqkh1
      complexed with man
    2. 781936Domain d1zlvm1: 1zlv M:1-112 [125264]
      Other proteins in same PDB: d1zlvh2, d1zlvm2
      automatically matched to d1aqkh1
      complexed with man
  16. Domain(s) for 1zlw:
    1. 781984Domain d1zlwh1: 1zlw H:1-112 [125266]
      Other proteins in same PDB: d1zlwh2, d1zlwm2
      automatically matched to d1aqkh1
      complexed with bma, man
    2. 781985Domain d1zlwm1: 1zlw M:1-112 [125268]
      Other proteins in same PDB: d1zlwh2, d1zlwm2
      automatically matched to d1aqkh1
      complexed with bma, man
  17. Domain(s) for 2fb4:
  18. Domain(s) for 2ghw:
    1. 781950Domain d2ghwb2: 2ghw B:1-117 [145199]
      Other proteins in same PDB: d2ghwa1, d2ghwb1, d2ghwc1, d2ghwd1
      complexed with cl
    2. 781951Domain d2ghwd2: 2ghw D:1-117 [145201]
      Other proteins in same PDB: d2ghwa1, d2ghwb1, d2ghwc1, d2ghwd1
      automatically matched to 2GHW B:1-117
      complexed with cl
  19. Domain(s) for 2ig2:
  20. Domain(s) for 2jb5:
  21. Domain(s) for 2jb6:
    1. 781980Domain d2jb6b1: 2jb6 B:3-120 [147957]
      Other proteins in same PDB: d2jb6b2, d2jb6h2
      automatically matched to d1nl0h1
      complexed with t5c
    2. 781981Domain d2jb6h1: 2jb6 H:3-120 [147959]
      Other proteins in same PDB: d2jb6b2, d2jb6h2
      automatically matched to d1nl0h1
      complexed with t5c
  22. Domain(s) for 2oqj:
    1. 781976Domain d2oqjb1: 2oqj B:1-112 [148984]
      Other proteins in same PDB: d2oqjb2, d2oqje2, d2oqjh2, d2oqjk2
      automatically matched to d1aqkh1
    2. 781977Domain d2oqje1: 2oqj E:1-112 [148986]
      Other proteins in same PDB: d2oqjb2, d2oqje2, d2oqjh2, d2oqjk2
      automatically matched to d1aqkh1
    3. 781978Domain d2oqjh1: 2oqj H:1-112 [148988]
      Other proteins in same PDB: d2oqjb2, d2oqje2, d2oqjh2, d2oqjk2
      automatically matched to d1aqkh1
    4. 781979Domain d2oqjk1: 2oqj K:1-112 [148990]
      Other proteins in same PDB: d2oqjb2, d2oqje2, d2oqjh2, d2oqjk2
      automatically matched to d1aqkh1
  23. Domain(s) for 2qqn:
  24. Domain(s) for 3b2u:
    1. 781956Domain d3b2uc1: 3b2u C:1-121 [154774]
      Other proteins in same PDB: d3b2ua1, d3b2ua2, d3b2ub1, d3b2ub2, d3b2uc2, d3b2ue1, d3b2ue2, d3b2uf2, d3b2uh2, d3b2ui1, d3b2ui2, d3b2uj2, d3b2um1, d3b2um2, d3b2un2, d3b2up1, d3b2up2, d3b2uq2, d3b2us1, d3b2us2, d3b2ut2, d3b2uv1, d3b2uv2, d3b2uw2
      automatically matched to d1deeb1
      complexed with bma, man, nag, so4
    2. 781957Domain d3b2uf1: 3b2u F:1-121 [154778]
      Other proteins in same PDB: d3b2ua1, d3b2ua2, d3b2ub1, d3b2ub2, d3b2uc2, d3b2ue1, d3b2ue2, d3b2uf2, d3b2uh2, d3b2ui1, d3b2ui2, d3b2uj2, d3b2um1, d3b2um2, d3b2un2, d3b2up1, d3b2up2, d3b2uq2, d3b2us1, d3b2us2, d3b2ut2, d3b2uv1, d3b2uv2, d3b2uw2
      automatically matched to d1deeb1
      complexed with bma, man, nag, so4
    3. 781958Domain d3b2uh1: 3b2u H:1-121 [154780]
      Other proteins in same PDB: d3b2ua1, d3b2ua2, d3b2ub1, d3b2ub2, d3b2uc2, d3b2ue1, d3b2ue2, d3b2uf2, d3b2uh2, d3b2ui1, d3b2ui2, d3b2uj2, d3b2um1, d3b2um2, d3b2un2, d3b2up1, d3b2up2, d3b2uq2, d3b2us1, d3b2us2, d3b2ut2, d3b2uv1, d3b2uv2, d3b2uw2
      automatically matched to d1deeb1
      complexed with bma, man, nag, so4
    4. 781959Domain d3b2uj1: 3b2u J:1-121 [154784]
      Other proteins in same PDB: d3b2ua1, d3b2ua2, d3b2ub1, d3b2ub2, d3b2uc2, d3b2ue1, d3b2ue2, d3b2uf2, d3b2uh2, d3b2ui1, d3b2ui2, d3b2uj2, d3b2um1, d3b2um2, d3b2un2, d3b2up1, d3b2up2, d3b2uq2, d3b2us1, d3b2us2, d3b2ut2, d3b2uv1, d3b2uv2, d3b2uw2
      automatically matched to d1deeb1
      complexed with bma, man, nag, so4
    5. 781960Domain d3b2un1: 3b2u N:1-121 [154788]
      Other proteins in same PDB: d3b2ua1, d3b2ua2, d3b2ub1, d3b2ub2, d3b2uc2, d3b2ue1, d3b2ue2, d3b2uf2, d3b2uh2, d3b2ui1, d3b2ui2, d3b2uj2, d3b2um1, d3b2um2, d3b2un2, d3b2up1, d3b2up2, d3b2uq2, d3b2us1, d3b2us2, d3b2ut2, d3b2uv1, d3b2uv2, d3b2uw2
      automatically matched to d1deeb1
      complexed with bma, man, nag, so4
    6. 781961Domain d3b2uq1: 3b2u Q:1-121 [154792]
      Other proteins in same PDB: d3b2ua1, d3b2ua2, d3b2ub1, d3b2ub2, d3b2uc2, d3b2ue1, d3b2ue2, d3b2uf2, d3b2uh2, d3b2ui1, d3b2ui2, d3b2uj2, d3b2um1, d3b2um2, d3b2un2, d3b2up1, d3b2up2, d3b2uq2, d3b2us1, d3b2us2, d3b2ut2, d3b2uv1, d3b2uv2, d3b2uw2
      automatically matched to d1deeb1
      complexed with bma, man, nag, so4
    7. 781962Domain d3b2ut1: 3b2u T:1-121 [154796]
      Other proteins in same PDB: d3b2ua1, d3b2ua2, d3b2ub1, d3b2ub2, d3b2uc2, d3b2ue1, d3b2ue2, d3b2uf2, d3b2uh2, d3b2ui1, d3b2ui2, d3b2uj2, d3b2um1, d3b2um2, d3b2un2, d3b2up1, d3b2up2, d3b2uq2, d3b2us1, d3b2us2, d3b2ut2, d3b2uv1, d3b2uv2, d3b2uw2
      automatically matched to d1deeb1
      complexed with bma, man, nag, so4
    8. 781963Domain d3b2uw1: 3b2u W:1-121 [154800]
      Other proteins in same PDB: d3b2ua1, d3b2ua2, d3b2ub1, d3b2ub2, d3b2uc2, d3b2ue1, d3b2ue2, d3b2uf2, d3b2uh2, d3b2ui1, d3b2ui2, d3b2uj2, d3b2um1, d3b2um2, d3b2un2, d3b2up1, d3b2up2, d3b2uq2, d3b2us1, d3b2us2, d3b2ut2, d3b2uv1, d3b2uv2, d3b2uw2
      automatically matched to d1deeb1
      complexed with bma, man, nag, so4
  25. Domain(s) for 3b2v:
  26. Domain(s) for 3bky:
  27. Domain(s) for 3c08:
  28. Domain(s) for 3c09:
    1. 781989Domain d3c09c1: 3c09 C:2-121 [155813]
      Other proteins in same PDB: d3c09a1, d3c09a2, d3c09c2, d3c09d1, d3c09d2, d3c09h2
      automatically matched to d8fabb1
      complexed with bma, man, nag
    2. 781990Domain d3c09h1: 3c09 H:2-121 [155817]
      Other proteins in same PDB: d3c09a1, d3c09a2, d3c09c2, d3c09d1, d3c09d2, d3c09h2
      automatically matched to d8fabb1
      complexed with bma, man, nag
  29. Domain(s) for 3cfj:
    1. 781945Domain d3cfjb1: 3cfj B:1-113 [156567]
      Other proteins in same PDB: d3cfja1, d3cfja2, d3cfjb2, d3cfjc1, d3cfjc2, d3cfjd2, d3cfje1, d3cfje2, d3cfjf2, d3cfjh2, d3cfjl1, d3cfjl2
      automatically matched to d1aqkh1
      complexed with gol, so4; mutant
    2. 781946Domain d3cfjd1: 3cfj D:1-113 [156571]
      Other proteins in same PDB: d3cfja1, d3cfja2, d3cfjb2, d3cfjc1, d3cfjc2, d3cfjd2, d3cfje1, d3cfje2, d3cfjf2, d3cfjh2, d3cfjl1, d3cfjl2
      automatically matched to d1aqkh1
      complexed with gol, so4; mutant
    3. 781947Domain d3cfjf1: 3cfj F:1-113 [156575]
      Other proteins in same PDB: d3cfja1, d3cfja2, d3cfjb2, d3cfjc1, d3cfjc2, d3cfjd2, d3cfje1, d3cfje2, d3cfjf2, d3cfjh2, d3cfjl1, d3cfjl2
      automatically matched to d1aqkh1
      complexed with gol, so4; mutant
    4. 781948Domain d3cfjh1: 3cfj H:1-113 [156577]
      Other proteins in same PDB: d3cfja1, d3cfja2, d3cfjb2, d3cfjc1, d3cfjc2, d3cfjd2, d3cfje1, d3cfje2, d3cfjf2, d3cfjh2, d3cfjl1, d3cfjl2
      automatically matched to d1aqkh1
      complexed with gol, so4; mutant
  30. Domain(s) for 3cfk:
    1. 781937Domain d3cfkb1: 3cfk B:1-113 [156583]
      Other proteins in same PDB: d3cfka1, d3cfka2, d3cfkb2, d3cfkc1, d3cfkc2, d3cfkd2, d3cfke1, d3cfke2, d3cfkf2, d3cfkg1, d3cfkg2, d3cfkh2, d3cfki2, d3cfkj1, d3cfkj2, d3cfkk2, d3cfkl1, d3cfkl2, d3cfkm1, d3cfkm2, d3cfkn2, d3cfko1, d3cfko2, d3cfkp2
      automatically matched to d1aqkh1
      complexed with b3p, cd, gol; mutant
    2. 781938Domain d3cfkd1: 3cfk D:1-113 [156587]
      Other proteins in same PDB: d3cfka1, d3cfka2, d3cfkb2, d3cfkc1, d3cfkc2, d3cfkd2, d3cfke1, d3cfke2, d3cfkf2, d3cfkg1, d3cfkg2, d3cfkh2, d3cfki2, d3cfkj1, d3cfkj2, d3cfkk2, d3cfkl1, d3cfkl2, d3cfkm1, d3cfkm2, d3cfkn2, d3cfko1, d3cfko2, d3cfkp2
      automatically matched to d1aqkh1
      complexed with b3p, cd, gol; mutant
    3. 781939Domain d3cfkf1: 3cfk F:1-113 [156591]
      Other proteins in same PDB: d3cfka1, d3cfka2, d3cfkb2, d3cfkc1, d3cfkc2, d3cfkd2, d3cfke1, d3cfke2, d3cfkf2, d3cfkg1, d3cfkg2, d3cfkh2, d3cfki2, d3cfkj1, d3cfkj2, d3cfkk2, d3cfkl1, d3cfkl2, d3cfkm1, d3cfkm2, d3cfkn2, d3cfko1, d3cfko2, d3cfkp2
      automatically matched to d1aqkh1
      complexed with b3p, cd, gol; mutant
    4. 781940Domain d3cfkh1: 3cfk H:1-113 [156595]
      Other proteins in same PDB: d3cfka1, d3cfka2, d3cfkb2, d3cfkc1, d3cfkc2, d3cfkd2, d3cfke1, d3cfke2, d3cfkf2, d3cfkg1, d3cfkg2, d3cfkh2, d3cfki2, d3cfkj1, d3cfkj2, d3cfkk2, d3cfkl1, d3cfkl2, d3cfkm1, d3cfkm2, d3cfkn2, d3cfko1, d3cfko2, d3cfkp2
      automatically matched to d1aqkh1
      complexed with b3p, cd, gol; mutant
    5. 781941Domain d3cfki1: 3cfk I:1-113 [156597]
      Other proteins in same PDB: d3cfka1, d3cfka2, d3cfkb2, d3cfkc1, d3cfkc2, d3cfkd2, d3cfke1, d3cfke2, d3cfkf2, d3cfkg1, d3cfkg2, d3cfkh2, d3cfki2, d3cfkj1, d3cfkj2, d3cfkk2, d3cfkl1, d3cfkl2, d3cfkm1, d3cfkm2, d3cfkn2, d3cfko1, d3cfko2, d3cfkp2
      automatically matched to d1aqkh1
      complexed with b3p, cd, gol; mutant
    6. 781942Domain d3cfkk1: 3cfk K:1-113 [156601]
      Other proteins in same PDB: d3cfka1, d3cfka2, d3cfkb2, d3cfkc1, d3cfkc2, d3cfkd2, d3cfke1, d3cfke2, d3cfkf2, d3cfkg1, d3cfkg2, d3cfkh2, d3cfki2, d3cfkj1, d3cfkj2, d3cfkk2, d3cfkl1, d3cfkl2, d3cfkm1, d3cfkm2, d3cfkn2, d3cfko1, d3cfko2, d3cfkp2
      automatically matched to d1aqkh1
      complexed with b3p, cd, gol; mutant
    7. 781943Domain d3cfkn1: 3cfk N:1-113 [156607]
      Other proteins in same PDB: d3cfka1, d3cfka2, d3cfkb2, d3cfkc1, d3cfkc2, d3cfkd2, d3cfke1, d3cfke2, d3cfkf2, d3cfkg1, d3cfkg2, d3cfkh2, d3cfki2, d3cfkj1, d3cfkj2, d3cfkk2, d3cfkl1, d3cfkl2, d3cfkm1, d3cfkm2, d3cfkn2, d3cfko1, d3cfko2, d3cfkp2
      automatically matched to d1aqkh1
      complexed with b3p, cd, gol; mutant
    8. 781944Domain d3cfkp1: 3cfk P:1-113 [156611]
      Other proteins in same PDB: d3cfka1, d3cfka2, d3cfkb2, d3cfkc1, d3cfkc2, d3cfkd2, d3cfke1, d3cfke2, d3cfkf2, d3cfkg1, d3cfkg2, d3cfkh2, d3cfki2, d3cfkj1, d3cfkj2, d3cfkk2, d3cfkl1, d3cfkl2, d3cfkm1, d3cfkm2, d3cfkn2, d3cfko1, d3cfko2, d3cfkp2
      automatically matched to d1aqkh1
      complexed with b3p, cd, gol; mutant
  31. Domain(s) for 3dvg:
  32. Domain(s) for 3dvn:
    1. 781965Domain d3dvnb1: 3dvn B:2-120 [157896]
      Other proteins in same PDB: d3dvna1, d3dvna2, d3dvnb2, d3dvnh2, d3dvnl1, d3dvnl2, d3dvnu1, d3dvnv1, d3dvnx1, d3dvny1
      automatically matched to d1nl0h1
      mutant
    2. 781966Domain d3dvnh1: 3dvn H:2-120 [157898]
      Other proteins in same PDB: d3dvna1, d3dvna2, d3dvnb2, d3dvnh2, d3dvnl1, d3dvnl2, d3dvnu1, d3dvnv1, d3dvnx1, d3dvny1
      automatically matched to d1nl0h1
      mutant
  33. Domain(s) for 8fab:
    1. 781921Domain d8fabb1: 8fab B:1-121 [19773]
      Other proteins in same PDB: d8faba1, d8faba2, d8fabb2, d8fabc1, d8fabc2, d8fabd2
      part of Fab HIL
    2. 781922Domain d8fabd1: 8fab D:1-121 [19775]
      Other proteins in same PDB: d8faba1, d8faba2, d8fabb2, d8fabc1, d8fabc2, d8fabd2
      part of Fab HIL

More info for Species Human (Homo sapiens), cluster 3 [TaxId:9606] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH

Timeline for Species Human (Homo sapiens), cluster 3 [TaxId:9606] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH: