![]() | Class b: All beta proteins [48724] (165 folds) |
![]() | Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies) sandwich; 7 strands in 2 sheets; greek-key some members of the fold have additional strands |
![]() | Superfamily b.1.1: Immunoglobulin [48726] (4 families) ![]() |
![]() | Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (29 proteins) |
![]() | Protein Immunoglobulin heavy chain variable domain, VH [88543] (20 species) VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species |
![]() | Species Human (Homo sapiens), cluster 3 [TaxId:9606] [88547] (19 PDB entries) |
![]() | Domain d1aqkh1: 1aqk H:1-123 [20193] Other proteins in same PDB: d1aqkh2, d1aqkl1, d1aqkl2 part of Fab B7-15A2 |
![]() | Domain d1deeb1: 1dee B:501-621 [20443] Other proteins in same PDB: d1deea1, d1deea2, d1deeb2, d1deec1, d1deec2, d1deed2, d1deee1, d1deee2, d1deef2, d1deeg_, d1deeh_ |
![]() | Domain d1deed1: 1dee D:1501-1621 [20445] Other proteins in same PDB: d1deea1, d1deea2, d1deeb2, d1deec1, d1deec2, d1deed2, d1deee1, d1deee2, d1deef2, d1deeg_, d1deeh_ |
![]() | Domain d1deef1: 1dee F:2501-2621 [20447] Other proteins in same PDB: d1deea1, d1deea2, d1deeb2, d1deec1, d1deec2, d1deed2, d1deee1, d1deee2, d1deef2, d1deeg_, d1deeh_ part of IgM RF 2A2 |
![]() | Domain d1dfbh1: 1dfb H:1-126 [19811] Other proteins in same PDB: d1dfbh2, d1dfbl1, d1dfbl2 part of Fab 3D6 |
![]() | Domain d1dqlh_: 1dql H: [19829] Other proteins in same PDB: d1dqll_ part of IgM Fv MEZ |
![]() | Domain d1igmh_: 1igm H: [19827] Other proteins in same PDB: d1igml_ part of IgM Fv POT |
![]() | Domain d1nl0h1: 1nl0 H:1-113 [91945] Other proteins in same PDB: d1nl0g_, d1nl0h2, d1nl0l1, d1nl0l2 part of Fab 10c12 against factor IX Gla domain complexed with ca, so4 |
![]() | Domain d1u6ah1: 1u6a H:2-113 [119564] Other proteins in same PDB: d1u6ah2, d1u6al1, d1u6al2 automatically matched to d1aqkh1 |
![]() | Domain d1w72h1: 1w72 H:1-113 [114299] Other proteins in same PDB: d1w72a1, d1w72a2, d1w72b_, d1w72d1, d1w72d2, d1w72e_, d1w72h2, d1w72i2, d1w72l1, d1w72l2, d1w72m1, d1w72m2 |
![]() | Domain d1w72i1: 1w72 I:1-113 [114301] Other proteins in same PDB: d1w72a1, d1w72a2, d1w72b_, d1w72d1, d1w72d2, d1w72e_, d1w72h2, d1w72i2, d1w72l1, d1w72l2, d1w72m1, d1w72m2 complexed with gol |
![]() | Domain d1y0lb1: 1y0l B:1-113 [122488] Other proteins in same PDB: d1y0la1, d1y0la2, d1y0lb2, d1y0lc1, d1y0lc2, d1y0ld2, d1y0le1, d1y0le2, d1y0lf2, d1y0lh2, d1y0ll1, d1y0ll2 automatically matched to d1aqkh1 complexed with cl, han |
![]() | Domain d1y0ld1: 1y0l D:1-113 [122492] Other proteins in same PDB: d1y0la1, d1y0la2, d1y0lb2, d1y0lc1, d1y0lc2, d1y0ld2, d1y0le1, d1y0le2, d1y0lf2, d1y0lh2, d1y0ll1, d1y0ll2 automatically matched to d1aqkh1 complexed with cl, han |
![]() | Domain d1y0lf1: 1y0l F:1-113 [122496] Other proteins in same PDB: d1y0la1, d1y0la2, d1y0lb2, d1y0lc1, d1y0lc2, d1y0ld2, d1y0le1, d1y0le2, d1y0lf2, d1y0lh2, d1y0ll1, d1y0ll2 automatically matched to d1aqkh1 complexed with cl, han |
![]() | Domain d1y0lh1: 1y0l H:1-113 [122498] Other proteins in same PDB: d1y0la1, d1y0la2, d1y0lb2, d1y0lc1, d1y0lc2, d1y0ld2, d1y0le1, d1y0le2, d1y0lf2, d1y0lh2, d1y0ll1, d1y0ll2 automatically matched to d1aqkh1 complexed with cl, han |
![]() | Domain d1y18b1: 1y18 B:1-113 [122523] Other proteins in same PDB: d1y18a1, d1y18a2, d1y18b2, d1y18c1, d1y18c2, d1y18d2, d1y18e1, d1y18e2, d1y18f2, d1y18h2, d1y18l1, d1y18l2 automatically matched to d1aqkh1 complexed with cl, han; mutant |
![]() | Domain d1y18d1: 1y18 D:1-113 [122527] Other proteins in same PDB: d1y18a1, d1y18a2, d1y18b2, d1y18c1, d1y18c2, d1y18d2, d1y18e1, d1y18e2, d1y18f2, d1y18h2, d1y18l1, d1y18l2 automatically matched to d1aqkh1 complexed with cl, han; mutant |
![]() | Domain d1y18f1: 1y18 F:1-113 [122531] Other proteins in same PDB: d1y18a1, d1y18a2, d1y18b2, d1y18c1, d1y18c2, d1y18d2, d1y18e1, d1y18e2, d1y18f2, d1y18h2, d1y18l1, d1y18l2 automatically matched to d1aqkh1 complexed with cl, han; mutant |
![]() | Domain d1y18h1: 1y18 H:1-113 [122533] Other proteins in same PDB: d1y18a1, d1y18a2, d1y18b2, d1y18c1, d1y18c2, d1y18d2, d1y18e1, d1y18e2, d1y18f2, d1y18h2, d1y18l1, d1y18l2 automatically matched to d1aqkh1 complexed with cl, han; mutant |
![]() | Domain d1zlsh1: 1zls H:1-112 [125255] Other proteins in same PDB: d1zlsh2 automatically matched to d1aqkh1 complexed with man |
![]() | Domain d1zluh1: 1zlu H:1-112 [125258] Other proteins in same PDB: d1zluh2, d1zlum2 automatically matched to d1aqkh1 complexed with man |
![]() | Domain d1zlum1: 1zlu M:1-112 [125260] Other proteins in same PDB: d1zluh2, d1zlum2 automatically matched to d1aqkh1 complexed with man |
![]() | Domain d1zlvh1: 1zlv H:1-112 [125262] Other proteins in same PDB: d1zlvh2, d1zlvm2 automatically matched to d1aqkh1 complexed with man |
![]() | Domain d1zlvm1: 1zlv M:1-112 [125264] Other proteins in same PDB: d1zlvh2, d1zlvm2 automatically matched to d1aqkh1 complexed with man |
![]() | Domain d1zlwh1: 1zlw H:1-112 [125266] Other proteins in same PDB: d1zlwh2, d1zlwm2 automatically matched to d1aqkh1 complexed with bma, man |
![]() | Domain d1zlwm1: 1zlw M:1-112 [125268] Other proteins in same PDB: d1zlwh2, d1zlwm2 automatically matched to d1aqkh1 complexed with bma, man |
![]() | Domain d2fb4h1: 2fb4 H:1-119 [19847] Other proteins in same PDB: d2fb4h2, d2fb4l1, d2fb4l2 part of Fab KOL |
![]() | Domain d2ig2h1: 2ig2 H:1-119 [19849] Other proteins in same PDB: d2ig2h2, d2ig2l1, d2ig2l2 part of antibody KOL; intact protein but only Fab's can be seen in the crystal structure |
Timeline for Species Human (Homo sapiens), cluster 3 [TaxId:9606] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH: