Lineage for Species: Human (Homo sapiens), cluster 5 [TaxId: 9606]

  1. Root: SCOPe 2.03
  2. 1287432Class b: All beta proteins [48724] (174 folds)
  3. 1287433Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1287434Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1287435Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 1289510Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
    VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family
  7. 1289591Species Human (Homo sapiens), cluster 5 [TaxId:9606] [88540] (7 PDB entries)
    Uniprot Q8N355 20-230 # 94% sequence identity; natural chimera: antibody light chain (Fab HYB3)

PDB entries in Species: Human (Homo sapiens), cluster 5 [TaxId: 9606]:

  1. Domain(s) for 1adq:
  2. Domain(s) for 1lil:
    1. 1289599Domain d1lila1: 1lil A:2-107 [20557]
      Other proteins in same PDB: d1lila2, d1lilb2
      part of Bence-Jones protein CLE
    2. 1289600Domain d1lilb1: 1lil B:2-107 [20558]
      Other proteins in same PDB: d1lila2, d1lilb2
      part of Bence-Jones protein CLE
  3. Domain(s) for 1w72:
    1. 1289594Domain d1w72l1: 1w72 L:1-107 [114303]
      Other proteins in same PDB: d1w72a1, d1w72a2, d1w72b_, d1w72d1, d1w72d2, d1w72e_, d1w72h1, d1w72h2, d1w72i1, d1w72i2, d1w72l2, d1w72m2
      complexed with gol
    2. 1289595Domain d1w72m1: 1w72 M:1-107 [114305]
      Other proteins in same PDB: d1w72a1, d1w72a2, d1w72b_, d1w72d1, d1w72d2, d1w72e_, d1w72h1, d1w72h2, d1w72i1, d1w72i2, d1w72l2, d1w72m2
      complexed with gol
  4. Domain(s) for 1zvo:
    1. 1289602Domain d1zvoa1: 1zvo A:3-108 [125710]
      Other proteins in same PDB: d1zvoa2, d1zvob2
      automatically matched to d1adql1
    2. 1289603Domain d1zvob1: 1zvo B:3-108 [125712]
      Other proteins in same PDB: d1zvoa2, d1zvob2
      automatically matched to d1adql1
  5. Domain(s) for 2dd8:
  6. Domain(s) for 2g75:
    1. 1289597Domain d2g75b1: 2g75 B:2-108 [147088]
      Other proteins in same PDB: d2g75a1, d2g75a2, d2g75b2, d2g75c1, d2g75c2, d2g75d2
      automated match to d2dd8l1
    2. 1289598Domain d2g75d1: 2g75 D:2-108 [147092]
      Other proteins in same PDB: d2g75a1, d2g75a2, d2g75b2, d2g75c1, d2g75c2, d2g75d2
      automated match to d2dd8l1
  7. Domain(s) for 8fab:
    1. 1289592Domain d8faba1: 8fab A:3-105 [19772]
      Other proteins in same PDB: d8faba2, d8fabb1, d8fabb2, d8fabc2, d8fabd1, d8fabd2
      part of Fab HIL
    2. 1289593Domain d8fabc1: 8fab C:3-105 [19774]
      Other proteins in same PDB: d8faba2, d8fabb1, d8fabb2, d8fabc2, d8fabd1, d8fabd2
      part of Fab HIL

More info for Species Human (Homo sapiens), cluster 5 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda

Timeline for Species Human (Homo sapiens), cluster 5 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda: