Lineage for Species: Human (Homo sapiens), cluster 5 [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2019185Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
    VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family
  7. 2019263Species Human (Homo sapiens), cluster 5 [TaxId:9606] [88540] (7 PDB entries)
    Uniprot Q8N355 20-230 # 94% sequence identity; natural chimera: antibody light chain (Fab HYB3)

PDB entries in Species: Human (Homo sapiens), cluster 5 [TaxId: 9606]:

  1. Domain(s) for 1adq:
  2. Domain(s) for 1lil:
    1. 2019271Domain d1lila1: 1lil A:2-107 [20557]
      Other proteins in same PDB: d1lila2, d1lilb2
      part of Bence-Jones protein CLE
    2. 2019272Domain d1lilb1: 1lil B:2-107 [20558]
      Other proteins in same PDB: d1lila2, d1lilb2
      part of Bence-Jones protein CLE
  3. Domain(s) for 1w72:
    1. 2019266Domain d1w72l1: 1w72 L:1-107 [114303]
      Other proteins in same PDB: d1w72a1, d1w72a2, d1w72b1, d1w72b2, d1w72d1, d1w72d2, d1w72e1, d1w72e2, d1w72h1, d1w72h2, d1w72i1, d1w72i2, d1w72l2, d1w72m2
      complexed with gol
    2. 2019267Domain d1w72m1: 1w72 M:1-107 [114305]
      Other proteins in same PDB: d1w72a1, d1w72a2, d1w72b1, d1w72b2, d1w72d1, d1w72d2, d1w72e1, d1w72e2, d1w72h1, d1w72h2, d1w72i1, d1w72i2, d1w72l2, d1w72m2
      complexed with gol
  4. Domain(s) for 1zvo:
    1. 2019274Domain d1zvoa1: 1zvo A:3-108 [125710]
      Other proteins in same PDB: d1zvoa2, d1zvob2
      automatically matched to d1adql1
    2. 2019275Domain d1zvob1: 1zvo B:3-108 [125712]
      Other proteins in same PDB: d1zvoa2, d1zvob2
      automatically matched to d1adql1
  5. Domain(s) for 2dd8:
  6. Domain(s) for 2g75:
    1. 2019269Domain d2g75b1: 2g75 B:2-108 [147088]
      Other proteins in same PDB: d2g75a1, d2g75a2, d2g75b2, d2g75c1, d2g75c2, d2g75d2
      automated match to d2dd8l1
    2. 2019270Domain d2g75d1: 2g75 D:2-108 [147092]
      Other proteins in same PDB: d2g75a1, d2g75a2, d2g75b2, d2g75c1, d2g75c2, d2g75d2
      automated match to d2dd8l1
  7. Domain(s) for 8fab:
    1. 2019264Domain d8faba1: 8fab A:3-105 [19772]
      Other proteins in same PDB: d8faba2, d8fabb1, d8fabb2, d8fabc2, d8fabd1, d8fabd2
      part of Fab HIL
    2. 2019265Domain d8fabc1: 8fab C:3-105 [19774]
      Other proteins in same PDB: d8faba2, d8fabb1, d8fabb2, d8fabc2, d8fabd1, d8fabd2
      part of Fab HIL

More info for Species Human (Homo sapiens), cluster 5 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda

Timeline for Species Human (Homo sapiens), cluster 5 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda: