SCOP 1.69: Species: Human (Homo sapiens), cluster 4

Lineage for Species: Human (Homo sapiens), cluster 4

Root: SCOP 1.69
Class b: All beta proteins [48724] (144 folds)
Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
sandwich; 7 strands in 2 sheets; greek-key
some members of the fold have additional strands
Superfamily b.1.1: Immunoglobulin [48726] (4 families)
Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (27 proteins)

Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family

Species Human (Homo sapiens), cluster 4 [TaxId:9606] [88539] (23 PDB entries)

PDB entries in Species: Human (Homo sapiens), cluster 4:

Domain(s) for 1a8j:
1. Domain d1a8jh1: 1a8j H:1-111 [20598]
  Other proteins in same PDB: d1a8jh2, d1a8jl2
  part of the antibody MCG light chain dimer
2. Domain d1a8jl1: 1a8j L:1-111 [20597]
  Other proteins in same PDB: d1a8jh2, d1a8jl2
Domain(s) for 1dcl:
1. Domain d1dcla1: 1dcl A:1-111 [20565]
  Other proteins in same PDB: d1dcla2, d1dclb2
2. Domain d1dclb1: 1dcl B:1-111 [20566]
  Other proteins in same PDB: d1dcla2, d1dclb2
  part of the antibody MCG light chain dimer
Domain(s) for 1jvk:
1. Domain d1jvka1: 1jvk A:1-112 [71897]
  Other proteins in same PDB: d1jvka2, d1jvkb2
2. Domain d1jvkb1: 1jvk B:1-112 [71899]
  Other proteins in same PDB: d1jvka2, d1jvkb2
  part of amyloidogenic protein BUR
Domain(s) for 1lgv:
1. Domain d1lgva1: 1lgv A:1-112 [84608]
  Other proteins in same PDB: d1lgva2, d1lgvb2
2. Domain d1lgvb1: 1lgv B:1-112 [84610]
  Other proteins in same PDB: d1lgva2, d1lgvb2
  part of amyloidogenic protein BUR
Domain(s) for 1lhz:
1. Domain d1lhza1: 1lhz A:1-112 [84612]
  Other proteins in same PDB: d1lhza2, d1lhzb2
2. Domain d1lhzb1: 1lhz B:1-112 [84614]
  Other proteins in same PDB: d1lhza2, d1lhzb2
  part of amyloidogenic protein BUR
Domain(s) for 1mcb:
1. Domain d1mcba1: 1mcb A:1-111 [20575]
  Other proteins in same PDB: d1mcba2, d1mcbb2
2. Domain d1mcbb1: 1mcb B:1-111 [20576]
  Other proteins in same PDB: d1mcba2, d1mcbb2
  part of the antibody MCG light chain dimer
Domain(s) for 1mcc:
1. Domain d1mcca1: 1mcc A:1-111 [20583]
  Other proteins in same PDB: d1mcca2, d1mccb2
2. Domain d1mccb1: 1mcc B:1-111 [20584]
  Other proteins in same PDB: d1mcca2, d1mccb2
  part of the antibody MCG light chain dimer
Domain(s) for 1mcd:
1. Domain d1mcda1: 1mcd A:1-111 [20571]
  Other proteins in same PDB: d1mcda2, d1mcdb2
2. Domain d1mcdb1: 1mcd B:1-111 [20572]
  Other proteins in same PDB: d1mcda2, d1mcdb2
  part of the antibody MCG light chain dimer
Domain(s) for 1mce:
1. Domain d1mcea1: 1mce A:1-111 [20587]
  Other proteins in same PDB: d1mcea2, d1mceb2
2. Domain d1mceb1: 1mce B:1-111 [20588]
  Other proteins in same PDB: d1mcea2, d1mceb2
  part of the antibody MCG light chain dimer
Domain(s) for 1mcf:
1. Domain d1mcfa1: 1mcf A:1-111 [20579]
  Other proteins in same PDB: d1mcfa2, d1mcfb2
2. Domain d1mcfb1: 1mcf B:1-111 [20580]
  Other proteins in same PDB: d1mcfa2, d1mcfb2
  part of the antibody MCG light chain dimer
Domain(s) for 1mch:
1. Domain d1mcha1: 1mch A:1-111 [20599]
  Other proteins in same PDB: d1mcha2, d1mchb2
2. Domain d1mchb1: 1mch B:1-111 [20600]
  Other proteins in same PDB: d1mcha2, d1mchb2
  part of the antibody MCG light chain dimer
Domain(s) for 1mci:
1. Domain d1mcia1: 1mci A:1-111 [20581]
  Other proteins in same PDB: d1mcia2, d1mcib2
2. Domain d1mcib1: 1mci B:1-111 [20582]
  Other proteins in same PDB: d1mcia2, d1mcib2
  part of the antibody MCG light chain dimer
Domain(s) for 1mcj:
1. Domain d1mcja1: 1mcj A:1-111 [20595]
  Other proteins in same PDB: d1mcja2, d1mcjb2
2. Domain d1mcjb1: 1mcj B:1-111 [20596]
  Other proteins in same PDB: d1mcja2, d1mcjb2
  part of the antibody MCG light chain dimer
Domain(s) for 1mck:
1. Domain d1mcka1: 1mck A:1-111 [20573]
  Other proteins in same PDB: d1mcka2, d1mckb2
2. Domain d1mckb1: 1mck B:1-111 [20574]
  Other proteins in same PDB: d1mcka2, d1mckb2
  part of the antibody MCG light chain dimer
Domain(s) for 1mcl:
1. Domain d1mcla1: 1mcl A:1-111 [20589]
  Other proteins in same PDB: d1mcla2, d1mclb2
2. Domain d1mclb1: 1mcl B:1-111 [20590]
  Other proteins in same PDB: d1mcla2, d1mclb2
  part of the antibody MCG light chain dimer
Domain(s) for 1mcn:
1. Domain d1mcna1: 1mcn A:1-111 [20591]
  Other proteins in same PDB: d1mcna2, d1mcnb2
2. Domain d1mcnb1: 1mcn B:1-111 [20592]
  Other proteins in same PDB: d1mcna2, d1mcnb2
  part of the antibody MCG light chain dimer
Domain(s) for 1mco:
- Domain d1mcol1: 1mco L:1-111 [20563]
  Other proteins in same PDB: d1mcoh1, d1mcoh2, d1mcoh3, d1mcoh4, d1mcol2
  part of intact antibody MCG
Domain(s) for 1mcq:
1. Domain d1mcqa1: 1mcq A:1-111 [20577]
  Other proteins in same PDB: d1mcqa2, d1mcqb2
2. Domain d1mcqb1: 1mcq B:1-111 [20578]
  Other proteins in same PDB: d1mcqa2, d1mcqb2
  part of the antibody MCG light chain dimer
Domain(s) for 1mcr:
1. Domain d1mcra1: 1mcr A:1-111 [20593]
  Other proteins in same PDB: d1mcra2, d1mcrb2
2. Domain d1mcrb1: 1mcr B:1-111 [20594]
  Other proteins in same PDB: d1mcra2, d1mcrb2
  part of the antibody MCG light chain dimer
Domain(s) for 1mcs:
1. Domain d1mcsa1: 1mcs A:1-111 [20585]
  Other proteins in same PDB: d1mcsa2, d1mcsb2
2. Domain d1mcsb1: 1mcs B:1-111 [20586]
  Other proteins in same PDB: d1mcsa2, d1mcsb2
  part of the antibody MCG light chain dimer
Domain(s) for 1mcw:
1. Domain d1mcwm1: 1mcw M:1-111 [20601]
  Other proteins in same PDB: d1mcwm2, d1mcww2
2. Domain d1mcww1: 1mcw W:1-111 [20602]
  Other proteins in same PDB: d1mcwm2, d1mcww2
  part of heterologous L chain dimer MCG-WEIR
Domain(s) for 2mcg:
1. Domain d2mcg11: 2mcg 1:1-111 [20567]
  Other proteins in same PDB: d2mcg12, d2mcg22
2. Domain d2mcg21: 2mcg 2:1-111 [20568]
  Other proteins in same PDB: d2mcg12, d2mcg22
  part of the antibody MCG light chain dimer
Domain(s) for 3mcg:
1. Domain d3mcg11: 3mcg 1:1-111 [20569]
  Other proteins in same PDB: d3mcg12, d3mcg22
2. Domain d3mcg21: 3mcg 2:1-111 [20570]
  Other proteins in same PDB: d3mcg12, d3mcg22
  part of the antibody MCG light chain dimer

More info for Species Human (Homo sapiens), cluster 4 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda

Timeline for Species Human (Homo sapiens), cluster 4 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda:

Species Human (Homo sapiens), cluster 4 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda first appeared in SCOP 1.65
Species Human (Homo sapiens), cluster 4 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda appears in SCOP 1.67
Species Human (Homo sapiens), cluster 4 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda appears in SCOP 1.71
Species Human (Homo sapiens), cluster 4 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda appears in the current release, SCOPe 2.08