Lineage for Species: Human (Homo sapiens), cluster 1

  1. Root: SCOP 1.71
  2. 546417Class b: All beta proteins [48724] (149 folds)
  3. 546418Fold b.1: Immunoglobulin-like beta-sandwich [48725] (25 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 546419Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 546420Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (28 proteins)
  6. 547970Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
    VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family
  7. 547974Species Human (Homo sapiens), cluster 1 [TaxId:9606] [88535] (4 PDB entries)

PDB entries in Species: Human (Homo sapiens), cluster 1:

  1. Domain(s) for 1cd0:
    1. 547977Domain d1cd0a_: 1cd0 A: [20559]
    2. 547978Domain d1cd0b_: 1cd0 B: [20560]
      VL dimer of Bence-Jones protein JTO
  2. Domain(s) for 1pew:
    1. 547975Domain d1pewa_: 1pew A: [104135]
    2. 547976Domain d1pewb_: 1pew B: [104136]
      complexed with cd; mutant
  3. Domain(s) for 1pw3:
    1. 547979Domain d1pw3a_: 1pw3 A: [104335]
    2. 547980Domain d1pw3b_: 1pw3 B: [104336]
      complexed with cd; mutant
  4. Domain(s) for 2cd0:
    1. 547981Domain d2cd0a_: 2cd0 A: [20561]
    2. 547982Domain d2cd0b_: 2cd0 B: [20562]
      VL dimer of Bence-Jones protein WIL

More info for Species Human (Homo sapiens), cluster 1 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda

Timeline for Species Human (Homo sapiens), cluster 1 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda: