Lineage for Species: Human (Homo sapiens), cluster 1

  1. Root: SCOP 1.69
  2. 450777Class b: All beta proteins [48724] (144 folds)
  3. 450778Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 450779Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 450780Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (27 proteins)
  6. 452262Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
    VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family
  7. 452266Species Human (Homo sapiens), cluster 1 [TaxId:9606] [88535] (4 PDB entries)

PDB entries in Species: Human (Homo sapiens), cluster 1:

  1. Domain(s) for 1cd0:
    1. 452269Domain d1cd0a_: 1cd0 A: [20559]
    2. 452270Domain d1cd0b_: 1cd0 B: [20560]
      VL dimer of Bence-Jones protein JTO
  2. Domain(s) for 1pew:
    1. 452267Domain d1pewa_: 1pew A: [104135]
    2. 452268Domain d1pewb_: 1pew B: [104136]
  3. Domain(s) for 1pw3:
    1. 452271Domain d1pw3a_: 1pw3 A: [104335]
    2. 452272Domain d1pw3b_: 1pw3 B: [104336]
  4. Domain(s) for 2cd0:
    1. 452273Domain d2cd0a_: 2cd0 A: [20561]
    2. 452274Domain d2cd0b_: 2cd0 B: [20562]
      VL dimer of Bence-Jones protein WIL

More info for Species Human (Homo sapiens), cluster 1 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda

Timeline for Species Human (Homo sapiens), cluster 1 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda: