Lineage for Species: Human (Homo sapiens), cluster 1 [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2019185Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
    VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family
  7. 2019189Species Human (Homo sapiens), cluster 1 [TaxId:9606] [88535] (4 PDB entries)
    SQ NA # Bence-Jones protein JTO ! Uniprot P06317 # Ig lambda chain V-VI region SUT

PDB entries in Species: Human (Homo sapiens), cluster 1 [TaxId: 9606]:

  1. Domain(s) for 1cd0:
    1. 2019192Domain d1cd0a_: 1cd0 A: [20559]
      VL dimer of Bence-Jones protein JTO
    2. 2019193Domain d1cd0b_: 1cd0 B: [20560]
      VL dimer of Bence-Jones protein JTO
  2. Domain(s) for 1pew:
    1. 2019190Domain d1pewa_: 1pew A: [104135]
      complexed with cd; mutant
    2. 2019191Domain d1pewb_: 1pew B: [104136]
      complexed with cd; mutant
  3. Domain(s) for 1pw3:
    1. 2019194Domain d1pw3a_: 1pw3 A: [104335]
      complexed with cd
    2. 2019195Domain d1pw3b_: 1pw3 B: [104336]
      complexed with cd
  4. Domain(s) for 2cd0:
    1. 2019196Domain d2cd0a_: 2cd0 A: [20561]
      VL dimer of Bence-Jones protein WIL
    2. 2019197Domain d2cd0b_: 2cd0 B: [20562]
      VL dimer of Bence-Jones protein WIL

More info for Species Human (Homo sapiens), cluster 1 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda

Timeline for Species Human (Homo sapiens), cluster 1 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda: