![]() | Class b: All beta proteins [48724] (126 folds) |
![]() | Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies) sandwich; 7 strands in 2 sheets; greek-key some members of the fold have additional strands |
![]() | Superfamily b.1.1: Immunoglobulin [48726] (4 families) ![]() |
![]() | Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (21 proteins) |
![]() | Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species) VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogeneous CDRs are listed as engineered species |
![]() | Species Human (Homo sapiens), cluster 3.1 [TaxId:9606] [88522] (4 PDB entries) |
![]() | Domain d1hzhl1: 1hzh L:1-107 [61445] Other proteins in same PDB: d1hzhh1, d1hzhh2, d1hzhh3, d1hzhh4, d1hzhk1, d1hzhk2, d1hzhk3, d1hzhk4, d1hzhl2, d1hzhm2 |
![]() | Domain d1hzhm1: 1hzh M:1-107 [61447] Other proteins in same PDB: d1hzhh1, d1hzhh2, d1hzhh3, d1hzhh4, d1hzhk1, d1hzhk2, d1hzhk3, d1hzhk4, d1hzhl2, d1hzhm2 part of intact IgG B12 antibody complexed with fuc, gal, man, nag |
![]() | Domain d1iqda1: 1iqd A:2-108 [62644] Other proteins in same PDB: d1iqda2, d1iqdb1, d1iqdb2, d1iqdc_ part of Fab BO2C11 against the C2 domain of factor VIII mutant |
Timeline for Species Human (Homo sapiens), cluster 3.1 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain kappa variable domain, VL-kappa: