Lineage for d2f5bl1 (2f5b L:1-107)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2018294Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (16 species)
    VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2018295Species Engineered (including hybrid species) [88533] (61 PDB entries)
    SQ NA # humanized antidoby; bactericidal Fab-h6831 ! SQ NA # Humanized antibody ! SQ NA # humanized antibody ! SQ NA # engineered antibody
  8. 2018311Domain d2f5bl1: 2f5b L:1-107 [88508]
    Other proteins in same PDB: d2f5bh1, d2f5bh2, d2f5bl2
    part of humanized HIV-1 neutralizing Fab 2F5

Details for d2f5bl1

PDB Entry: 2f5b (more details), 2 Å

PDB Description: crystal structure of fab' from the hiv-1 neutralizing antibody 2f5 in complex with its gp41 epitope
PDB Compounds: (L:) protein (antibody 2f5 (light chain))

SCOPe Domain Sequences for d2f5bl1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2f5bl1 b.1.1.1 (L:1-107) Immunoglobulin light chain kappa variable domain, VL-kappa {Engineered (including hybrid species)}

SCOPe Domain Coordinates for d2f5bl1:

Click to download the PDB-style file with coordinates for d2f5bl1.
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Timeline for d2f5bl1:

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