SCOPe 2.08: Domain d1uoma_: 1uom A:

Lineage for d1uoma_ (1uom A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (107 PDB entries)
   Uniprot P03372 307-551

8. Domain d1uoma_: 1uom A: [88497]
   protein/DNA complex; complexed with pti

Details for d1uoma_

PDB Entry: 1uom, 2.28 Å

PDB Description: the structure of estrogen receptor in complex with a selective and potent tetrahydroisochiolin ligand.

PDB Compounds: (A:) Estrogen receptor

SCOPe Domain Sequences for d1uoma_:

Sequence, based on SEQRES records:

>d1uoma_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvpg
fvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifd
mllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtl
ihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvplydlllemlda
h

Sequence, based on observed residues (ATOM records):

>d1uoma_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvpg
fvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifd
mllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtl
ihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlplydlllemldah

Timeline for d1uoma_:

• d1uoma_ first appeared in SCOP 1.65
  
• d1uoma_ appears in SCOPe 2.07