SCOPe 2.08: Domain d1ub0a_: 1ub0 A:

Lineage for d1ub0a_ (1ub0 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.72: Ribokinase-like [53612] (3 superfamilies)
   core: 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 21345678, strand 7 is antiparallel to the rest
   potential superfamily: members of this fold have similar functions but different ATP-binding sites

4. Superfamily c.72.1: Ribokinase-like [53613] (6 families)
   has extra strand located between strands 2 and 3

5. Family c.72.1.2: Thiamin biosynthesis kinases [53620] (2 proteins)

6. Protein 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) [69589] (2 species)

7. Species Thermus thermophilus [TaxId:274] [89775] (1 PDB entry)

8. Domain d1ub0a_: 1ub0 A: [88394]
   structural genomics
   complexed with dio, gol, so4

Details for d1ub0a_

PDB Entry: 1ub0, 2.05 Å

PDB Description: Crystal Structure Analysis of Phosphomethylpyrimidine Kinase (ThiD) from Thermus Thermophilus Hb8

PDB Compounds: (A:) phosphomethylpyrimidine kinase

SCOPe Domain Sequences for d1ub0a_:

Sequence, based on SEQRES records:

>d1ub0a_ c.72.1.2 (A:) 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) {Thermus thermophilus [TaxId: 274]}
mrvaltiagsdsgggagvqadlkvffrfgvygtsaltlvtaqntlgvqrvhllppevvya
qiesvaqdfplhaaktgalgdaaiveavaeavrrfgvrplvvdpvmvaksgdpllakeaa
aalkerlfpladlvtpnrleaeallgrpirtlkeaeeaakallalgpkavllkgghlege
eavdllatrggvlrfsaprvhtrnthgtgctlsaaiaallakgrplaeavaeakayltra
lktapslghghgpldhwa

Sequence, based on observed residues (ATOM records):

>d1ub0a_ c.72.1.2 (A:) 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) {Thermus thermophilus [TaxId: 274]}
mrvaltiagsdsgggagvqadlkvffrfgvygtsaltlvtaqntlgvqrvhllppevvya
qiesvaqdfplhaaktgalgdaaiveavaeavrrfgvrplvvdpvmakeaaaalkerlfp
ladlvtpnrleaeallgrpirtlkeaeeaakallalgpkavllkgghleavdllatrggv
lrfsaprvhtrnthgtgctlsaaiaallakgrplaeavaeakayltralktapslghghg
pldhwa

Timeline for d1ub0a_:

• d1ub0a_ first appeared in SCOP 1.65
  
• d1ub0a_ appears in SCOPe 2.07