SCOPe 2.05: Domain d1uama_: 1uam A:

Lineage for d1uama_ (1uam A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.116: alpha/beta knot [75216] (1 superfamily)
   core: 3 layers: a/b/a, parallel beta-sheet of 5 strands, order 21435; contains a deep trefoil knot

4. Superfamily c.116.1: alpha/beta knot [75217] (9 families)
   known or predicted SAM-dependent methytransferases including the SPOUT 'sequence' superfamily
   all known members have dimeric structures

5. Family c.116.1.4: tRNA(m1G37)-methyltransferase TrmD [89629] (2 proteins)
   fold and dimerisation mode are similar to those of the YbeA-like family; contains additional C-terminal all-alpha subdomain

6. Protein tRNA(m1G37)-methyltransferase TrmD [89630] (3 species)

7. Species Haemophilus influenzae [TaxId:727] [89631] (4 PDB entries)

8. Domain d1uama_: 1uam A: [88384]
   complexed with po4, sah

Details for d1uama_

PDB Entry: 1uam, 2.2 Å

PDB Description: Crystal structure of tRNA(m1G37)methyltransferase: Insight into tRNA recognition

PDB Compounds: (A:) tRNA (guanine-N(1)-)-methyltransferase

SCOPe Domain Sequences for d1uama_:

Sequence, based on SEQRES records:

>d1uama_ c.116.1.4 (A:) tRNA(m1G37)-methyltransferase TrmD {Haemophilus influenzae [TaxId: 727]}
shmwigvislfpemfkaitefgvtgravkhnllkvecwnprdftfdkhktvddrpygggp
gmlmmvqplrdaihtakaaagegakviylspqgrkldqggvtelaqnqklilvcgryegi
derliqteideewsigdyvltggelpamtlidavarfipgvlgkqasaeedsfadglldc
phytrpevlegltvppvlmsghheeirkwrlkqslqrtwlrrpelleglaltdeqrkllk
eaqaehnslehh

Sequence, based on observed residues (ATOM records):

>d1uama_ c.116.1.4 (A:) tRNA(m1G37)-methyltransferase TrmD {Haemophilus influenzae [TaxId: 727]}
shmwigvislfpemfkaitefgvtgravkhnllkvecwnprdftfdkhktvddrpygggp
gmlmmvqplrdaihtakaaagegakviylspqgrkldqggvtelaqnqklilvcgryegi
derliqteideewsigdyvltggelpamtlidavarfipgvlgkqaeedsfadglldcph
ytrpevlegltvppvlmsghheeirkwrlkqslqrtwlrrpelleglaltdeqrkllkea
qaehnslehh

Timeline for d1uama_:

• d1uama_ first appeared in SCOP 1.65
  
• d1uama_ appears in SCOPe 2.04
  
• d1uama_ is called d1uama1 in SCOPe 2.06
  
• d1uama_ appears in the current release, SCOPe 2.08, called d1uama1