Class c: Alpha and beta proteins (a/b) [51349] (121 folds) |
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465 |
Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules |
Family c.36.1.6: TK-like Pyr module [88735] (2 proteins) different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain |
Protein Transketolase (TK), Pyr module [88736] (3 species) |
Species Escherichia coli [TaxId:562] [89650] (1 PDB entry) |
Domain d1qgda1: 1qgd A:333-527 [88367] Other proteins in same PDB: d1qgda2, d1qgda3, d1qgdb2, d1qgdb3 |
PDB Entry: 1qgd (more details), 1.9 Å
SCOP Domain Sequences for d1qgda1:
Sequence; same for both SEQRES and ATOM records: (download)
>d1qgda1 c.36.1.6 (A:333-527) Transketolase (TK), Pyr module {Escherichia coli} mpsdfdakakefiaklqanpakiasrkasqnaieafgpllpeflggsadlapsnltlwsg skainedaagnyihygvrefgmtaiangislhggflpytstflmfveyarnavrmaalmk qrqvmvythdsiglgedgpthqpveqvaslrvtpnmstwrpcdqvesavawkygverqdg ptalilsrqnlaqqe
Timeline for d1qgda1: