Lineage for d1pkqf2 (1pkq F:108-210)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2020524Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 protein domains)
  6. 2023413Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)
  7. 2023414Species Human (Homo sapiens) [TaxId:9606] [88569] (144 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
    SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody
  8. 2023599Domain d1pkqf2: 1pkq F:108-210 [88154]
    Other proteins in same PDB: d1pkqa1, d1pkqb1, d1pkqb2, d1pkqe1, d1pkqe2, d1pkqf1, d1pkqg1, d1pkqg2, d1pkqj1, d1pkqj2
    part of humanized Fab 8-18c5

Details for d1pkqf2

PDB Entry: 1pkq (more details), 3 Å

PDB Description: Myelin Oligodendrocyte Glycoprotein-(8-18C5) Fab-complex
PDB Compounds: (F:) (8-18C5) chimeric Fab, light chain

SCOPe Domain Sequences for d1pkqf2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1pkqf2 b.1.1.2 (F:108-210) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1pkqf2:

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Timeline for d1pkqf2: