SCOP 1.65: Domain d1pb3a_: 1pb3 A:

Lineage for d1pb3a_ (1pb3 A:)

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.77: Isocitrate/Isopropylmalate dehydrogenases [53658] (1 superfamily)
   consists of two intertwined (sub)domains related by pseudo dyad; duplication
   3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenases [53659] (2 families)

5. Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (3 proteins)
   the active site is between the two identical subunits

6. Protein Isocitrate dehydrogenase, ICDH [53668] (2 species)

7. Species Escherichia coli [TaxId:562] [53669] (26 PDB entries)

8. Domain d1pb3a_: 1pb3 A: [88015]
   complexed with gol, so4

Details for d1pb3a_

PDB Entry: 1pb3, 1.7 Å

PDB Description: sites of binding and orientation in a four location model for protein stereospecificity.

SCOP Domain Sequences for d1pb3a_:

Sequence; same for both SEQRES and ATOM records:

>d1pb3a_ c.77.1.1 (A:) Isocitrate dehydrogenase, ICDH {Escherichia coli}
meskvvvpaqgkkitlqngklnvpenpiipyiegdgigvdvtpamlkvvdaavekaykge
rkiswmeiytgekstqvygqdvwlpaetldlireyrvaikgplttpvgggirslnvalrq
eldlyiclrpvryyqgtpspvkhpeltdmvifrensediyagiewkadsadaekvikflr
eemgvkkirfpehcgigikpcseegtkrlvraaieyaiandrdsvtlvhkgnimkftega
fkdwgyqlareefggelidggpwlkvknpntgkeivikdviadaflqqillrpaeydvia
cmnlngdyisdalaaqvggigiapganigdecalfeathgtapkyagqdkvnpgsiilsa
emmlrhmgwteaadlivkgmegainaktvtydferlmdgakllkcsefgdaiienm

Timeline for d1pb3a_:

• d1pb3a_ is new in SCOP 1.65
  
• d1pb3a_ appears in SCOP 1.67
  
• d1pb3a_ appears in the current release, SCOPe 2.08