SCOPe 2.06: Domain d1p8jc2: 1p8j C:109-442

Lineage for d1p8jc2 (1p8j C:109-442)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.41: Subtilisin-like [52742] (1 superfamily)
   3 layers: a/b/a, parallel beta-sheet of 7 strands, order 2314567; left-handed crossover connection between strands 2 & 3

4. Superfamily c.41.1: Subtilisin-like [52743] (3 families)

5. Family c.41.1.1: Subtilases [52744] (14 proteins)

6. Protein Furin, N-terminal domain [89694] (1 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [89695] (1 PDB entry)

8. Domain d1p8jc2: 1p8j C:109-442 [87951]
   Other proteins in same PDB: d1p8ja1, d1p8jb1, d1p8jc1, d1p8jd1, d1p8je1, d1p8jf1, d1p8jg1, d1p8jh1
   complexed with ca, nag, so4

Details for d1p8jc2

PDB Entry: 1p8j, 2.6 Å

PDB Description: crystal structure of the proprotein convertase furin

PDB Compounds: (C:) Furin precursor

SCOPe Domain Sequences for d1p8jc2:

Sequence; same for both SEQRES and ATOM records:

>d1p8jc2 c.41.1.1 (C:109-442) Furin, N-terminal domain {Mouse (Mus musculus) [TaxId: 10090]}
vyqeptdpkfpqqwylsgvtqrdlnvkeawaqgftghgivvsilddgieknhpdlagnyd
pgasfdvndqdpdpqprytqmndnrhgtrcagevaavanngvcgvgvaynariggvrmld
gevtdavearslglnpnhihiysaswgpeddgktvdgparlaeeaffrgvsqgrgglgsi
fvwasgnggrehdscncdgytnsiytlsissatqfgnvpwyseacsstlattyssgnqne
kqivttdlrqkcteshtgtsasaplaagiialtleanknltwrdmqhlvvqtskpahlna
ddwatngvgrkvshsygyglldagamvalaqnwt

Timeline for d1p8jc2:

• d1p8jc2 first appeared in SCOP 1.65
  
• d1p8jc2 appears in SCOPe 2.05
  
• d1p8jc2 appears in SCOPe 2.07
  
• d1p8jc2 appears in the current release, SCOPe 2.08