SCOP 1.75: Domain d1p62b_: 1p62 B:

Lineage for d1p62b_ (1p62 B:)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (24 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (20 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Deoxycytidine kinase [89657] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89658] (7 PDB entries)

8. Domain d1p62b_: 1p62 B: [87819]
   complexed with adp, geo, mo3

Details for d1p62b_

PDB Entry: 1p62, 1.9 Å

PDB Description: Structure of human dCK complexed with gemcitabine and ADP-MG

PDB Compounds: (B:) Deoxycytidine kinase

SCOP Domain Sequences for d1p62b_:

Sequence, based on SEQRES records:

>d1p62b_ c.37.1.1 (B:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}
rikkisiegniaagkstfvnilkqlcedwevvpepvarwcnvqstqdefeeltmsqkngg
nvlqmmyekperwsftfqtyaclsriraqlaslngklkdaekpvlffersvysdryifas
nlyesecmnetewtiyqdwhdwmnnqfgqsleldgiiylqatpetclhriylrgrneeqg
ipleyleklhykheswllhrtlktnfdylqevpiltldvnedfkdkyeslvekvkeflst
l

Sequence, based on observed residues (ATOM records):

>d1p62b_ c.37.1.1 (B:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}
rikkisiegniaagkstfvnilkqlcedwevvpepvarwcnvqstnggnvlqmmyekper
wsftfqtyaclsriraqlaslngklkdaekpvlffersvysdryifasnlyesecmnete
wtiyqdwhdwmnnqfgqsleldgiiylqatpetclhriylrgrneeqgipleyleklhyk
heswllhrtlktnfdylqevpiltldvnedfkdkyeslvekvkeflstl

Timeline for d1p62b_:

• d1p62b_ first appeared in SCOP 1.65
  
• d1p62b_ appears in SCOP 1.73
  
• d1p62b_ appears in SCOPe 2.01
  
• d1p62b_ appears in the current release, SCOPe 2.08