Lineage for d1p22b2 (1p22 B:2-59)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2945442Fold d.42: POZ domain [54694] (1 superfamily)
    core: beta(2)-alpha(2)-beta(2)-alpha(2); 2 layers a/b; mixed sheet: 2143
  4. 2945443Superfamily d.42.1: POZ domain [54695] (3 families) (S)
  5. 2945444Family d.42.1.1: BTB/POZ domain [54696] (6 proteins)
  6. 2945520Protein Cyclin A/CDK2-associated p45, Skp1 [54710] (1 species)
  7. 2945521Species Human (Homo sapiens) [TaxId:9606] [54711] (9 PDB entries)
  8. 2945538Domain d1p22b2: 1p22 B:2-59 [87718]
    Other proteins in same PDB: d1p22a1, d1p22a2, d1p22a3, d1p22b1
    missing some secondary structures that made up less than one-third of the common domain

Details for d1p22b2

PDB Entry: 1p22 (more details), 2.95 Å

PDB Description: Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity on the SCFbeta-TrCP1 ubiquitin ligase
PDB Compounds: (B:) skp1

SCOPe Domain Sequences for d1p22b2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1p22b2 d.42.1.1 (B:2-59) Cyclin A/CDK2-associated p45, Skp1 {Human (Homo sapiens) [TaxId: 9606]}
psiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthh

SCOPe Domain Coordinates for d1p22b2:

Click to download the PDB-style file with coordinates for d1p22b2.
(The format of our PDB-style files is described here.)

Timeline for d1p22b2: