Lineage for d1p14a_ (1p14 A:)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1929110Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1929111Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1929232Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1930676Protein Insulin receptor [56162] (1 species)
    PTK group; InsR subfamily; membrane spanning protein tyrosine kinase
  7. 1930677Species Human (Homo sapiens) [TaxId:9606] [56163] (16 PDB entries)
  8. 1930681Domain d1p14a_: 1p14 A: [87660]
    mutant

Details for d1p14a_

PDB Entry: 1p14 (more details), 1.9 Å

PDB Description: Crystal structure of a catalytic-loop mutant of the insulin receptor tyrosine kinase
PDB Compounds: (A:) Insulin receptor

SCOPe Domain Sequences for d1p14a_:

Sequence, based on SEQRES records: (download)

>d1p14a_ d.144.1.7 (A:) Insulin receptor {Human (Homo sapiens) [TaxId: 9606]}
vfpssvyvpdewevsrekitllrelgqgsfgmvyegnardiikgeaetrvavktvnesas
lrerieflneasvmkgftchhvvrllgvvskgqptlvvmelmahgdlksylrslrpeaen
npgrppptlqemiqmaaeiadgmaylnakkfvhrnlaarncmvahdftvkigdfgmtrdi
yetdyyrkggkgllpvrwmapeslkdgvfttssdmwsfgvvlweitslaeqpyqglsneq
vlkfvmdggyldqpdncpervtdlmrmcwqfnpnmrptfleivnllkddlhpsfpevsff
hseenk

Sequence, based on observed residues (ATOM records): (download)

>d1p14a_ d.144.1.7 (A:) Insulin receptor {Human (Homo sapiens) [TaxId: 9606]}
vfpssvyvpdewevsrekitllrelgqgsfgmvyegnardiikgeaetrvavktvnesas
lrerieflneasvmkgftchhvvrllgvvskgqptlvvmelmahgdlksylrslrpeaen
npgrppptlqemiqmaaeiadgmaylnakkfvhrnlaarncmvahdftvkigdfgpvrwm
apeslkdgvfttssdmwsfgvvlweitslaeqpyqglsneqvlkfvmdggyldqpdncpe
rvtdlmrmcwqfnpnmrptfleivnllkddlhpsfpevsffhseenk

SCOPe Domain Coordinates for d1p14a_:

Click to download the PDB-style file with coordinates for d1p14a_.
(The format of our PDB-style files is described here.)

Timeline for d1p14a_: