SCOP 1.75: Domain d1oync_: 1oyn C:

Lineage for d1oync_ (1oyn C:)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (5 families)

5. Family a.211.1.2: PDEase [48548] (6 proteins)
   Pfam PF00233; multihelical; can be divided into three subdomains

6. Protein Catalytic domain of cyclic nucleotide phosphodiesterase pde4d [89151] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89152] (22 PDB entries)
   Uniprot Q08499 388-713

8. Domain d1oync_: 1oyn C: [87611]

Details for d1oync_

PDB Entry: 1oyn, 2 Å

PDB Description: Crystal structure of PDE4D2 in complex with (R,S)-rolipram

PDB Compounds: (C:) cAMP-specific phosphodiesterase PDE4D2

SCOP Domain Sequences for d1oync_:

Sequence; same for both SEQRES and ATOM records:

>d1oync_ a.211.1.2 (C:) Catalytic domain of cyclic nucleotide phosphodiesterase pde4d {Human (Homo sapiens) [TaxId: 9606]}
teqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkipvdtlity
lmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasaihdvdhp
gvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrqslrkmvi
divlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhcadlsnptkp
lqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivhplwetwa
dlvhpdaqdildtlednrewyqstipq

Timeline for d1oync_:

• d1oync_ first appeared in SCOP 1.65
  
• d1oync_ appears in SCOP 1.73
  
• d1oync_ appears in SCOPe 2.01
  
• d1oync_ appears in the current release, SCOPe 2.08