SCOP 1.71: Domain d1osnd_: 1osn D:

Lineage for d1osnd_ (1osn D:)

1. Root: SCOP 1.71

2. Class c: Alpha and beta proteins (a/b) [51349] (134 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (23 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (18 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Thymidine kinase [52552] (3 species)
   contains insert all-alpha subdomain, res. 251-322

7. Species Varicella-zoster virus [TaxId:10335] [89659] (1 PDB entry)

8. Domain d1osnd_: 1osn D: [87390]
   complexed with adp, bvp

Details for d1osnd_

PDB Entry: 1osn, 3.2 Å

PDB Description: Crystal structure of Varicella zoster virus thymidine kinase in complex with BVDU-MP and ADP

SCOP Domain Sequences for d1osnd_:

Sequence, based on SEQRES records:

>d1osnd_ c.37.1.1 (D:) Thymidine kinase {Varicella-zoster virus}
vkmgvlriyldgaygigkttaaeeflhhfaitpnrilligeplsywrnlagedaicgiyg
tqtrrlngdvspedaqrltahfqslfcsphaimhakisalmdtstsdlvqvnkepykiml
sdrhpiasticfplsrylvgdmspaalpgllftlpaeppgtnlvvctvslpshlsrvskr
arpgetvnlpfvmvlrnvyimlintiiflktnnwhagwntlsfcndvfkqklqksecikl
revpgiedtlfavlklpelcgefgnilplwawgmetlsnclrsmspfvlsleqtpqhaaq
elktllpqmtpanmssgawnilkelvnavqd

Sequence, based on observed residues (ATOM records):

>d1osnd_ c.37.1.1 (D:) Thymidine kinase {Varicella-zoster virus}
vkmgvlriyldgaygigkttaaeeflhhfaitpnrilligeplsywrnlagedaicgiyg
tqtrrlngdvspedaqrltahfqslfcsphaimhakisalmdtstepykimlsdrhpias
ticfplsrylvgdmspaalpgllftlpaeppgtnlvvctvslpshlsrvtvnlpfvmvlr
nvyimlintiiflktnnwhagwntlsfcndvfkqklqkseciklrevpgiedtlfavlkl
pelcgefgnilplwawgmetlsnclrsmspfvlsleqtpqhaaqelktllpqmtpanmss
gawnilkelvnavqd

Timeline for d1osnd_:

• d1osnd_ first appeared in SCOP 1.65
  
• d1osnd_ appears in SCOP 1.69
  
• d1osnd_ appears in SCOP 1.73
  
• d1osnd_ appears in the current release, SCOPe 2.08