SCOPe 2.05: Domain d1osnb_: 1osn B:

Lineage for d1osnb_ (1osn B:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Thymidine kinase [52552] (3 species)
   contains insert all-alpha subdomain, res. 251-322

7. Species Varicella-Zoster virus [TaxId:10335] [89659] (1 PDB entry)

8. Domain d1osnb_: 1osn B: [87388]
   complexed with adp, bvp

Details for d1osnb_

PDB Entry: 1osn, 3.2 Å

PDB Description: Crystal structure of Varicella zoster virus thymidine kinase in complex with BVDU-MP and ADP

PDB Compounds: (B:) Thymidine kinase

SCOPe Domain Sequences for d1osnb_:

Sequence, based on SEQRES records:

>d1osnb_ c.37.1.1 (B:) Thymidine kinase {Varicella-Zoster virus [TaxId: 10335]}
mgvlriyldgaygigkttaaeeflhhfaitpnrilligeplsywrnlagedaicgiygtq
trrlngdvspedaqrltahfqslfcsphaimhakisalmdtstsdlvqvnkepykimlsd
rhpiasticfplsrylvgdmspaalpgllftlpaeppgtnlvvctvslpshlsrvskrar
pgetvnlpfvmvlrnvyimlintiiflktnnwhagwntlsfcndvfkqklqkseciklre
vpgiedtlfavlklpelcgefgnilplwawgmetlsnclrsmspfvlsleqtpqhaaqel
ktllpqmtpanmssgawnilkelvnavqd

Sequence, based on observed residues (ATOM records):

>d1osnb_ c.37.1.1 (B:) Thymidine kinase {Varicella-Zoster virus [TaxId: 10335]}
mgvlriyldgaygigkttaaeeflhhfaitpnrilligeplsywrnlagedaicgiygtq
trrlngdvspedaqrltahfqslfcsphaimhakisalmdtstepykimlsdrhpiasti
cfplsrylvgdmspaalpgllftlpaeppgtnlvvctvslpshlsrvsetvnlpfvmvlr
nvyimlintiiflktnnwhagwntlsfcndvfkqklqkseciklrevpgiedtlfavlkl
pelcgefgnilplwawgmetlsnclrsmspfvlsleqtpqhaaqelktllpqmtpanmss
gawnilkelvnavqd

Timeline for d1osnb_:

• d1osnb_ first appeared in SCOP 1.65
  
• d1osnb_ appears in SCOPe 2.04
  
• d1osnb_ appears in SCOPe 2.06
  
• d1osnb_ appears in the current release, SCOPe 2.08