SCOP 1.69: Domain d1op5l1: 1op5 L:2-107

Lineage for d1op5l1 (1op5 L:2-107)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (27 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Engineered (including hybrid species) [88533] (31 PDB entries)

8. Domain d1op5l1: 1op5 L:2-107 [87220]
   Other proteins in same PDB: d1op5h1, d1op5h2, d1op5k2, d1op5l2, d1op5m1, d1op5m2
   part of engineered Fab 2G12

Details for d1op5l1

PDB Entry: 1op5, 3 Å

PDB Description: crystal structure of fab 2g12 bound to man9glcnac2

SCOP Domain Sequences for d1op5l1:

Sequence; same for both SEQRES and ATOM records:

>d1op5l1 b.1.1.1 (L:2-107) Immunoglobulin light chain kappa variable domain, VL-kappa {Engineered (including hybrid species)}
vvmtqspstlsasvgdtititcrasqsietwlawyqqkpgkapklliykastlktgvpsr
fsgsgsgteftltisglqfddfatyhcqhyagysatfgqgtrveik

Timeline for d1op5l1:

• d1op5l1 first appeared in SCOP 1.65
  
• d1op5l1 appears in SCOP 1.67
  
• d1op5l1 appears in SCOP 1.71
  
• d1op5l1 last appears in SCOPe 2.07