SCOPe 2.08: Domain d1onfa1: 1onf A:1-153,A:271-376

Lineage for d1onfa1 (1onf A:1-153,A:271-376)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
   core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander

4. Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (9 families)

5. Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (25 proteins)
   duplication: both domains have similar folds and functions
   most members of the family contain common C-terminal alpha+beta domain

6. Protein Glutathione reductase, N- and C-terminal domain [418942] (3 species)

7. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [419398] (1 PDB entry)

8. Domain d1onfa1: 1onf A:1-153,A:271-376 [87141]
   Other proteins in same PDB: d1onfa2, d1onfa3
   complexed with fad
   has additional insertions and/or extensions that are not grouped together

Details for d1onfa1

PDB Entry: 1onf, 2.6 Å

PDB Description: Crystal structure of Plasmodium falciparum Glutathione reductase

PDB Compounds: (A:) glutathione reductase

SCOPe Domain Sequences for d1onfa1:

Sequence, based on SEQRES records:

>d1onfa1 c.3.1.5 (A:1-153,A:271-376) Glutathione reductase, N- and C-terminal domain {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
vydlivigggsggmaaarraarhnakvalveksrlggtcvnvgcvpkkimfnaasvhdil
ensrhygfdtkfsfnlpllverrdkyiqrlnniyrqnlskdkvdlyegtasflsenrili
kgtkdnnnkdngplneeilegrniliavgnkpvXgrspdtenlkleklnvetnnnyivvd
enqrtsvnniyavgdccmvkkskeiedlnllklyneerylnkkenvtedifynvqltpva
inagrlladrlflkktrktn

Sequence, based on observed residues (ATOM records):

>d1onfa1 c.3.1.5 (A:1-153,A:271-376) Glutathione reductase, N- and C-terminal domain {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
vydlivigggsggmaaarraarhnakvalveksrlggtcvnvgcvpkkimfnaasvhdil
ensrhygfdtkfsfnlpllverrdkyiqrlnniyrqnlskdkvdlyegtasflegrnili
avgnkpvXgrspdtenlkleklnvetnnnyivvdenqrtsvnniyavgdccmvkfynvql
tpvainagrlladrlflkktrktn

Timeline for d1onfa1:

• d1onfa1 first appeared in SCOP 1.65
  
• d1onfa1 appears in SCOPe 2.07