SCOP 1.65: Domain d1onba_: 1onb A:

Lineage for d1onba_ (1onb A:)

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (21 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.14: RNA helicase [52724] (1 protein)
   duplication: consists of two similar domains, one binds NTP and the other binds RNA; also contains an all-alpha subdomain in the C-terminal extension

6. Protein HCV helicase domain [52725] (1 species)

7. Species Human hepatitis C virus (HCV), different isolates [TaxId:11103] [52726] (6 PDB entries)

8. Domain d1onba_: 1onb A: [87137]
   an engineered arginine-rich subdomain 2

Details for d1onba_

PDB Entry: 1onb

PDB Description: solution structure of an engineered arginine-rich subdomain 2 of the hepatitis c virus ns3 rna helicase

SCOP Domain Sequences for d1onba_:

Sequence; same for both SEQRES and ATOM records:

>d1onba_ c.37.1.14 (A:) HCV helicase domain {Human hepatitis C virus (HCV), different isolates}
gsvtvphpnieevalsttgeipfygkaiplevikggrhlifchskkkcdelaaklvalgi
navayyrgldvsviptngdvvvvatdalmtgftgdfdsvidcntsdgkpqdavsrtqrrg
rtgrgkpgiyrfvapger

Timeline for d1onba_:

• d1onba_ is new in SCOP 1.65
  
• d1onba_ appears in SCOP 1.67
  
• d1onba_ appears in the current release, SCOPe 2.08