SCOP 1.65: Domain d1on8b_: 1on8 B:

Lineage for d1on8b_ (1on8 B:)

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.68: Nucleotide-diphospho-sugar transferases [53447] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 7 strands, order 3214657; strand 6 is antiparallel to the rest

4. Superfamily c.68.1: Nucleotide-diphospho-sugar transferases [53448] (13 families)

5. Family c.68.1.15: Exostosin [89760] (1 protein)

6. Protein Alpha-1,4-N-acetylhexosaminyltransferase (Alpha-GalNAcT EXTL2) [89761] (1 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [89762] (4 PDB entries)

8. Domain d1on8b_: 1on8 B: [87124]
   complexed with edo, gal, gcu, mn, udp

Details for d1on8b_

PDB Entry: 1on8, 2.7 Å

PDB Description: crystal structure of mouse alpha-1,4-n-acetylhexosaminyltransferase (extl2) with udp and glcuab(1-3)galb(1-o)-naphthalenelmethanol an acceptor substrate analog

SCOP Domain Sequences for d1on8b_:

Sequence, based on SEQRES records:

>d1on8b_ c.68.1.15 (B:) Alpha-1,4-N-acetylhexosaminyltransferase (Alpha-GalNAcT EXTL2) {Mouse (Mus musculus)}
aldsftlimqtynrtdlllrllnhyqavpslhkvivvwnnvgekgpeelwnslgphpipv
ifkpqtankmrnrlqvfpevetnavlmvdddtlisaqdlvfafsiwqqfpdqiigfvprk
hvstssgiysyggfelqtpgpgngdqysmvligasffnskylelfqkqpaavhalidetq
ncddiamnflvtrhtgkpsgifvkpinmvnleketngysgmwhraehflqrsycinklvn
iydgmplkysnimisqfgfpyanhk

Sequence, based on observed residues (ATOM records):

>d1on8b_ c.68.1.15 (B:) Alpha-1,4-N-acetylhexosaminyltransferase (Alpha-GalNAcT EXTL2) {Mouse (Mus musculus)}
aldsftlimqtynrtdlllrllnhyqavpslhkvivvwnnvgekgpeelwnslgphpipv
ifkpqtankmrnrlqvfpevetnavlmvdddtlisaqdlvfafsiwqqfpdqiigfvprk
hvstssgiysyggfelqtpgpgngdqysmvligasffnskylelfqkqpaavhalidetq
ncddiamnflvtrhtgkpsgifvkpinmvnleketsgmwhraehflqrsycinklvniyd
gmplkysnimisqfgfpyanhk

Timeline for d1on8b_:

• d1on8b_ is new in SCOP 1.65
  
• d1on8b_ appears in SCOP 1.67
  
• d1on8b_ appears in the current release, SCOPe 2.08